Study on the mechanism of electroacupuncture scalp point penetration therapy in action on apoptosis in the Parkinson's disease rat model

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Study on the mechanism of electroacupuncture scalp point penetration therapy in action on apoptosis in the Parkinson's disease rat model

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- Study on the mechanism of electroacupuncture scalp point penetration therapy in action on apoptosis in the Parkinson's disease rat model
- Chinese Acupuncture and Moxibustion Vol. 29, Issue 4, Pages: 309-313(2009)
- 作者机构：
  
  1. 黑龙江省中医研究院针灸科
  2. 甘肃省中医院
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Published：2009
- 稿件说明：
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Study on the mechanism of electroacupuncture scalp point penetration therapy in action on apoptosis in the Parkinson's disease rat model[J]. Chinese Acupuncture and Moxibustion, 2009, 29(4): 309-313.
DOI：

Study on the mechanism of electroacupuncture scalp point penetration therapy in action on apoptosis in the Parkinson's disease rat model[J]. Chinese Acupuncture and Moxibustion, 2009, 29(4): 309-313. DOI：

摘要

目的:探讨头部电针透穴治疗帕金森病(PD)的作用机制。方法:将40只Wistar大鼠随机分为正常组、假手术组、模型组、针刺组

以6-羟基多巴胺(6-0HDA)左侧纹状体注射法制备偏侧PD大鼠模型

针刺组穴取"百会"透"太阳"

每日1次

6日为一疗程。其他3组不予治疗

观察2个疗程。采用免疫组织化学方法观察各组左侧黑质神经营养因子(BDNF)面密度(阳性目标总面积与统计场总面积比值)、积分光密度

用高效液相色谱观察左侧纹状体多巴胺(DA)含量

以TUNEL法观察各组细胞凋亡数。结果:针刺组与模型组比较

左侧黑质BDNF面密度、积分光密度均显著增大(P<0.05);细胞凋亡数量为(23.80±3.83)个

显著减少(P<0.05);纹状体DA含量显著增多(P<0.05)。结论:头部电针透穴可能是通过增强黑质BDNF蛋白表达水平来减少细胞凋亡数量。

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Effect of electroacupuncture scalp point-through-point therapy on the expression of tyrosine hydroxylase and dopamine transporter mRNAs in substantia nigra of Parkinson’s disease model rats

Effects of head point-through-point electroacupuncture on SOD and LPO in the patient of Parkinson's disease

Clinical observation on point-through-point therapy of scalp electroacupuncture for treatment of facial spasm

Clinical observation on head point-through-point electroacupuncture for treatment of poststroke depression

电针头穴配合语言训练治疗中风失语症的临床观察

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