Responses of glucose-sensitive neurons and insulin-sensitive neurons in nucleus tractus solitarius to electroacupuncture at auricular concha in rats

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Responses of glucose-sensitive neurons and insulin-sensitive neurons in nucleus tractus solitarius to electroacupuncture at auricular concha in rats

更新时间：2023-05-10

- Responses of glucose-sensitive neurons and insulin-sensitive neurons in nucleus tractus solitarius to electroacupuncture at auricular concha in rats
- Chinese Acupuncture and Moxibustion Issue 12, Pages: 917-922(2007)
- 作者机构：
  
  中国中医科学院针灸研究所
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- Published：2007
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Responses of glucose-sensitive neurons and insulin-sensitive neurons in nucleus tractus solitarius to electroacupuncture at auricular concha in rats[J]. Chinese Acupuncture and Moxibustion, 2007, (12): 917-922.
DOI：

Responses of glucose-sensitive neurons and insulin-sensitive neurons in nucleus tractus solitarius to electroacupuncture at auricular concha in rats[J]. Chinese Acupuncture and Moxibustion, 2007, (12): 917-922. DOI：

摘要

目的:初步探讨耳针降糖作用的中枢机制。方法:微电极胞外记录孤束核(NTS)神经元活动

将记录的细胞随机分为颈静脉注射葡萄糖组、胰岛素组及耳甲电针组

观察上述处理因素对各组神经元放电活动的影响。结果:NTS存在葡萄糖敏感和胰岛素敏感神经元

葡萄糖敏感神经元中抑制型占37.3%

兴奋型占10.9%;胰岛素敏感神经元中兴奋型占33.3%

抑制型占4.9%;电针耳甲

NTS神经元有49.3%(34/69)放电频率增加

4.3%(3/69)放电频率减少

34个耳针激活细胞中有18个对葡萄糖呈抑制反应

8个对胰岛素呈兴奋反应。结论:耳甲电针能兴奋NTS葡萄糖敏感神经元(抑制反应型为主)和胰岛素敏感神经元(激活反应型为主)

耳针的降糖效应可能与调节上述神经元放电活动有关。

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