Effect of electroacupuncture on gastric mucosal intestinal trefoil factor gene expression in the rat of gastric mucosal injury induced by stress

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Effect of electroacupuncture on gastric mucosal intestinal trefoil factor gene expression in the rat of gastric mucosal injury induced by stress

更新时间：2023-05-10

- Effect of electroacupuncture on gastric mucosal intestinal trefoil factor gene expression in the rat of gastric mucosal injury induced by stress
- Chinese Acupuncture and Moxibustion Issue 1, Pages: 66-68(2006)
- 作者机构：
  
  湖南中医学院针灸推拿系
- 作者简介：
- 基金信息：
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- Published：2006
- 稿件说明：
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Effect of electroacupuncture on gastric mucosal intestinal trefoil factor gene expression in the rat of gastric mucosal injury induced by stress[J]. Chinese Acupuncture and Moxibustion, 2006, (1): 66-68.
DOI：

Effect of electroacupuncture on gastric mucosal intestinal trefoil factor gene expression in the rat of gastric mucosal injury induced by stress[J]. Chinese Acupuncture and Moxibustion, 2006, (1): 66-68. DOI：

摘要

目的:探讨电针预处理对胃黏膜损伤大鼠胃黏膜组织肠三叶因子(intestinaltrefoilfactor

ITF)基因表达的影响及意义。方法:将40只大鼠随机分为空白组、模型组、胃经组、胆经组。空白组不做任何处理

而模型组仅捆缚7d后造模

胃经组、胆经组须先捆缚电针7d后再造模。造模采用水浸束缚法

水浸束缚10h

经相应处理后检测胃黏膜损伤指数(UI)

同时取各组大鼠胃黏膜组织

采用RTPCR方法测胃黏膜组织肠三叶因子基因(ITFmRNA)表达。结果:①胃经组、胆经组与模型组的UI比较差异有显著或非常显著性意义(P<0.05或P<0.01)

说明造模成功;②电针可提高胃黏膜组织ITFmRNA表达水平

胆经组较模型组ITFmRNA表达增高

胃经组较胆经组ITFmRNA表达非常显著升高(P<0.01)。结论:电针对胃黏膜组织特异性调整作用

与肠三叶因子基因表达差异有关。

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