Acupuncture inhibiting responses of spinal dorsal horn neurons induced by noxious dilation of rectum and colon

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Acupuncture inhibiting responses of spinal dorsal horn neurons induced by noxious dilation of rectum and colon

更新时间：2023-05-10

- Acupuncture inhibiting responses of spinal dorsal horn neurons induced by noxious dilation of rectum and colon
- Chinese Acupuncture and Moxibustion Issue 9, Pages: 645-650(2005)
- 作者机构：
  
  中国中医研究院针灸研究所
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Published：2005
- 稿件说明：
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Acupuncture inhibiting responses of spinal dorsal horn neurons induced by noxious dilation of rectum and colon[J]. Chinese Acupuncture and Moxibustion, 2005, (9): 645-650.
DOI：

Acupuncture inhibiting responses of spinal dorsal horn neurons induced by noxious dilation of rectum and colon[J]. Chinese Acupuncture and Moxibustion, 2005, (9): 645-650. DOI：

摘要

目的:探讨针灸缓解内脏痛的机制。方法:选用SD大鼠

采用直结肠扩张(CRD)作为内脏的伤害性刺激。微电极细胞外记录L1～L3节段脊髓背角广动力型神经元活动。针刺选用与直结肠同神经节段支配的同侧和对侧“足三里”穴位。结果:内脏伤害性传入能明显激活脊髓背角会聚神经元

对侧体表机械刺激和“足三里”穴位手针刺激可抑制这种伤害性反应。急性脊髓化实验

针刺对侧“足三里”穴位抑制CRD反应的效应完全消失。结论:针刺和内脏伤害性传入信号在脊髓水平发生会聚和相互作用

针刺穴位能够抑制内脏伤害性传入所激活的背角神经元反应

且这种作用需要脊髓上中枢参与。

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