Effect of electroacupuncture at "Neiguan" (PC 6) on expression of c-fos gene in myocardium of the rat with acute myocardial ischemia

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Effect of electroacupuncture at "Neiguan" (PC 6) on expression of c-fos gene in myocardium of the rat with acute myocardial ischemia

更新时间：2023-05-10

- Effect of electroacupuncture at "Neiguan" (PC 6) on expression of c-fos gene in myocardium of the rat with acute myocardial ischemia
- Chinese Acupuncture and Moxibustion Issue 5, Pages: 355-358(2005)
- 作者机构：
  
  1. 北京中医药大学附属中西医结合医院
  2. 华中科技大学同济医学院,武汉,430030
- 作者简介：
- 基金信息：
- DOI：
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- Published：2005
- 稿件说明：
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Effect of electroacupuncture at "Neiguan" (PC 6) on expression of c-fos gene in myocardium of the rat with acute myocardial ischemia[J]. Chinese Acupuncture and Moxibustion, 2005, (5): 355-358.
DOI：

Effect of electroacupuncture at "Neiguan" (PC 6) on expression of c-fos gene in myocardium of the rat with acute myocardial ischemia[J]. Chinese Acupuncture and Moxibustion, 2005, (5): 355-358. DOI：

摘要

目的:探讨电针“内关”改善急性心肌缺血的机制。方法:将96只大鼠随机分为假手术组、心肌缺血模型组、心肌缺血模型加电针组

采用结扎冠状动脉左前降支建立急性心肌缺血实验模型

造模成功后

电针双侧“内关”。用生化方法检测血清心肌酶活性

逆转录聚合酶链反应(RT-PCR)方法检测心肌中c-fos基因的表达。结果:心肌缺血模型组血清心肌酶活性和心肌c-fosmR—NA表达显著高于假手术组(P<0.05)

电针后降低

差异有显著性意义(P<0.05)。结论:电针“内关”改善急性心肌缺血的机制与下调心肌组织c—fosmRNA的表达有关。

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