Effects of acupuncture on IL-8 and sICAM-1 levels in cerebral fluid of patients with severely traumatic brain injury

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Effects of acupuncture on IL-8 and sICAM-1 levels in cerebral fluid of patients with severely traumatic brain injury

更新时间：2023-05-10

- Effects of acupuncture on IL-8 and sICAM-1 levels in cerebral fluid of patients with severely traumatic brain injury
- Chinese Acupuncture and Moxibustion Issue 7, (2004)
- 作者机构：
  
  1. 南京医科大学附属脑科医院神经外科
  2. 深圳市人民医院神经外科
- 作者简介：
- 基金信息：
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- Published：2004
- 稿件说明：
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Effects of acupuncture on IL-8 and sICAM-1 levels in cerebral fluid of patients with severely traumatic brain injury[J]. Chinese Acupuncture and Moxibustion, 2004, (7).
DOI：

Effects of acupuncture on IL-8 and sICAM-1 levels in cerebral fluid of patients with severely traumatic brain injury[J]. Chinese Acupuncture and Moxibustion, 2004, (7). DOI：

摘要

目的 :观察针刺对重度颅脑损伤患者脑脊液中白细胞介素 8(IL 8)、可溶性细胞黏附分子 1(sICAM 1)含量的影响

并探讨针刺治疗的脑保护作用机理。方法 :将 5 0例重度颅脑损伤患者随机分为对照组 2 4例和治疗组 2 6例。对照组应用西医常规治疗

治疗组在常规治疗基础上加针刺涌泉和厉兑穴。采用酶联免疫吸附方法 (ELISA)检测患者伤后 1、2、3、5、7d脑脊液中IL 8、sICAM 1含量。结果 :①对照组脑脊液中IL 8、sICAM 1含量在伤后 1d升高

2d达高峰

3d开始下降

5d进一步下降

7d下降到正常水平 ;②治疗组脑脊液中IL 8、sICAM 1含量在伤后 1d升高

2d下降

3d继续下降

5d下降到正常水平 ;③治疗组伤后 2、3、5d脑脊液中IL 8、sICAM 1含量均低于对照组(P <0 0 5 )。结论 :针刺能减轻重度颅脑损伤后脑内炎症反应

从而减轻因炎症反应引起的继发性脑损害。

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