Clinical observation on acupuncture for diarrhea-predominant irritable bowel syndrome patients in syndrome of liver-stagnation and spleen-deficiency and its impact on Th1/Th2

doi:10.13703/j.0255-2930.2013.12.003

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Clinical observation on acupuncture for diarrhea-predominant irritable bowel syndrome patients in syndrome of liver-stagnation and spleen-deficiency and its impact on Th1/Th2

更新时间：2023-05-10

- Clinical observation on acupuncture for diarrhea-predominant irritable bowel syndrome patients in syndrome of liver-stagnation and spleen-deficiency and its impact on Th1/Th2
- Chinese Acupuncture and Moxibustion Vol. 33, Issue 12, Pages: 1057-1060(2013)
- 作者机构：
  
  1. 南京中医药大学附属医院针灸康复科
  2. 南京中医药大学第二临床医学院
- 作者简介：
- 基金信息：
- DOI：10.13703/j.0255-2930.2013.12.003
  CLC：
- Published：2013
- 稿件说明：
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Clinical observation on acupuncture for diarrhea-predominant irritable bowel syndrome patients in syndrome of liver-stagnation and spleen-deficiency and its impact on Th1/Th2[J]. Chinese Acupuncture and Moxibustion, 2013, 33(12): 1057-1060.
DOI：

Clinical observation on acupuncture for diarrhea-predominant irritable bowel syndrome patients in syndrome of liver-stagnation and spleen-deficiency and its impact on Th1/Th2[J]. Chinese Acupuncture and Moxibustion, 2013, 33(12): 1057-1060. DOI： 10.13703/j.0255-2930.2013.12.003.

摘要

目的:观察针刺治疗腹泻型肠易激综合征肝郁脾虚证患者的临床疗效及其对细胞因子的影响。方法:纳入40例患者

随机分为两组。针刺组21例

予针刺治疗

穴取天枢、足三里、上巨虚等

每日1次;药物组19例

予口服得舒特及双岐杆菌乳杆菌三联活菌胶囊治疗。分别在治疗1周、2周、4周后比较两组治疗前后症状评分、血清Th1型细胞因子[γ型干扰素(IFN-γ)、白介素2(IL-2)]和Th2型细胞因子(IL-4、IL-10)含量以及IFN-γ/IL-4的比值等。结果:针刺组治疗1周后临床症状即有改善(P<0.05)

较药物组临床起效快(P<0.05);针刺组总有效率为90.48%(19/21)

优于药物组的78.95%(15/19

P<0.05);与药物相比较

患者Th1/Th2失衡状态经针刺后明显向Th2方向转化

有恢复平衡趋势。结论:针刺对D-IBS的临床疗效与其能有效促进D-IBS肝郁脾虚证患者Th1/Th2平衡密切相关。

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