Regulation action and nerve electrophysiology mechanism of acupuncture on arousal state in patients of primary insomnia

doi:10.13703/j.0255-2930.2017.01.004

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Regulation action and nerve electrophysiology mechanism of acupuncture on arousal state in patients of primary insomnia

更新时间：2023-05-10

- Regulation action and nerve electrophysiology mechanism of acupuncture on arousal state in patients of primary insomnia
- Chinese Acupuncture and Moxibustion Vol. 37, Issue 1, Pages: 19-23(2017)
- 作者机构：
  
  1. 杭州市第七人民医院心理科
  2. 杭州市红十字会医院
- 作者简介：
- 基金信息：
- DOI：10.13703/j.0255-2930.2017.01.004
  CLC：
- Published：2017
- 稿件说明：
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Regulation action and nerve electrophysiology mechanism of acupuncture on arousal state in patients of primary insomnia[J]. Chinese Acupuncture and Moxibustion, 2017, 37(1): 19-23.
DOI：

Regulation action and nerve electrophysiology mechanism of acupuncture on arousal state in patients of primary insomnia[J]. Chinese Acupuncture and Moxibustion, 2017, 37(1): 19-23. DOI： 10.13703/j.0255-2930.2017.01.004.

摘要

目的:比较针刺与艾司唑仑调节原发性失眠症患者觉醒状态的差异

并探讨其相关神经电生理学效应。方法:将64例原发性失眠症患者随机分为针刺组(32例)和药物组(32例)

共剔除3例

最终针刺组31例

药物组30例。针刺组主穴取四神聪、安眠、神门、三阴交、照海、申脉

结合配穴针刺治疗

每天1次

每周5次

连续治疗4周;药物组口服艾司唑仑片

每天1次

连续服用4周。观察两组治疗前后匹兹堡睡眠质量指数(Pittsburgh sleep quality index

PSQI)评分及多次睡眠潜伏时间试验(multiple sleep latency test

MSLT)的平均睡眠潜伏时间(mean sleep latency

MSL)

并采用多导睡眠监测仪(polysomnography

PSG)监测睡眠结构相关指标。结果:两组治疗后PSQI评分较治疗前均明显降低(均P<0.01)

针刺组治疗后PSQI评分较药物组降低幅度更大(P<0.05)。与治疗前比较

两组治疗后睡眠潜伏期(sleep onset latency

SOL)缩短、觉醒次数(number of awakenings

NWAK)、入睡后清醒时间(wake after sleep onset

WASO)减少

总睡眠时间(total sleep time

TST)增多、睡眠效率(sleep efficiency

SE)明显增高(均P<0.01)。药物组治疗后非快速眼动1/2/3期(non-rapid eye movement period 1/2/3

N1、N2、N3)、快速眼动睡眠期(rapid eye movement period

REM)占TST比例与治疗前比较差异无统计学意义(均P>0.05)。针刺组治疗后较治疗前N1、N2比例减少

N3、REM比例增多(均P<0.01);针刺组治疗后较药物组N1、N2比例减少

N3、REM比例增多(均P<0.01)。两组治疗后SOL、NWAK、WASO、TST、SE比较差异均无统计学意义(均P>0.05)。两组治疗后MSLT的MSL较治疗前均明显缩短(均P<0.01)

针刺组治疗后MSLT的MSL较药物组缩短更显著(P<0.05)。结论:针刺较艾司唑仑能更有效地改善原发性失眠症患者的睡眠质量

并更有利于调节其过度觉醒状态。

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