Effects of “Tongdu Tiaoshen” acupuncture on cerebral blood flow in patients with high risk of cerebral ischemic stroke based on ASL and PWI technique

doi:10.13703/j.0255-2930.2018.09.001

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Effects of “Tongdu Tiaoshen” acupuncture on cerebral blood flow in patients with high risk of cerebral ischemic stroke based on ASL and PWI technique

更新时间：2023-05-10

- Effects of “Tongdu Tiaoshen” acupuncture on cerebral blood flow in patients with high risk of cerebral ischemic stroke based on ASL and PWI technique
- Chinese Acupuncture and Moxibustion Vol. 38, Issue 9, Pages: 913-917(2018)
- 作者机构：
  
  1. 安徽中医药大学第二附属医院康复科
  2. 安徽中医药大学第二附属医院脑病科
- 作者简介：
- 基金信息：
- DOI：10.13703/j.0255-2930.2018.09.001
  CLC：
- Published：2018
- 稿件说明：
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Effects of “Tongdu Tiaoshen” acupuncture on cerebral blood flow in patients with high risk of cerebral ischemic stroke based on ASL and PWI technique[J]. Chinese Acupuncture and Moxibustion, 2018, 38(9): 913-917.
DOI：

Effects of “Tongdu Tiaoshen” acupuncture on cerebral blood flow in patients with high risk of cerebral ischemic stroke based on ASL and PWI technique[J]. Chinese Acupuncture and Moxibustion, 2018, 38(9): 913-917. DOI： 10.13703/j.0255-2930.2018.09.001.

摘要

目的:通过动脉自旋标记(ASL)和磁共振灌注成像(PWI)技术观察通督调神针刺与西药对缺血性脑卒中(CIS)高危患者脑血流的影响并评价其临床疗效。方法:将180例短暂性脑缺血发作(TIA)/缺血性小卒中(MIS)患者随机分成针刺1组、针刺2组和药物组

每组60例。针刺1组予以"通督调神针刺法"

穴取百会、风府、哑门、大椎、身柱、至阳、命门、腰阳关、颈夹脊

每天针刺1次;针刺2组取穴同针刺1组

隔天针刺1次;药物组予口服尼莫地平片

每次30 mg

早中晚各1片。3组均治疗4周。分别于治疗前后对患者行ASL、PWI(相对脑血容量(rCBV)、相对脑血流量(rCBF)、相对平均通过时间(rMTT)、相对达峰时间(rTTP))检测

比较治疗前后各项检测指标的变化

并评定疗效。结果:治疗后

3组患者ASL正常灌注例数较治疗前明显增多(均P<0.01)

针刺1组正常灌注例数多于针刺2组(P<0.05)

与药物组比较差异无统计学意义(P>0.05)。治疗后

3组患者rCBV、rCBF均较治疗前明显升高(均P<0.01)

rMTT、rTTP均较治疗前明显降低(均P<0.01);针刺1组治疗后rCBV、rCBF高于针刺2组

rMTT、rTTP低于针刺2组(均P<0.05);针刺1组与药物组相比

治疗后PWI各参数差异无统计学意义(均P>0.05)。针刺1组、针刺2组和药物组总有效率分别是88.3%(53/60)、73.3%(44/60)与90.0%(54/60)

针刺1组总有效率优于针刺2组(P<0.05)

与药物组比较差异无统计学意义(P>0.05)。结论:通督调神针刺干预能有效改善CIS高危患者脑血流低灌注情况

降低严重CIS的发病率

且针刺每天1次优于隔天1次。

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