Naochang Tongtiao acupuncture based on brain-gut axis for acute ischemic stroke and its effect on levels of IL-17, hs-CRP and TMAO

doi:10.13703/j.0255-2930.20210821-k0004

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Naochang Tongtiao acupuncture based on brain-gut axis for acute ischemic stroke and its effect on levels of IL-17, hs-CRP and TMAO

更新时间：2023-05-10

- Naochang Tongtiao acupuncture based on brain-gut axis for acute ischemic stroke and its effect on levels of IL-17, hs-CRP and TMAO
- Chinese Acupuncture and Moxibustion Vol. 42, Issue 8, Pages: 853-856(2022)
- 作者机构：
  
  1. 甘肃中医药大学附属医院针灸科
  2. 甘肃省皇甫谧针灸医院
  3. 甘肃中医药大学附属医院康复骨科
  4. 甘肃中医药大学针灸推拿学院
- 作者简介：
- 基金信息：
- DOI：10.13703/j.0255-2930.20210821-k0004
  CLC：
- Published：2022
- 稿件说明：
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Naochang Tongtiao acupuncture based on brain-gut axis for acute ischemic stroke and its effect on levels of IL-17, hs-CRP and TMAO[J]. Chinese Acupuncture and Moxibustion, 2022, 42(8): 853-856.
DOI：

Naochang Tongtiao acupuncture based on brain-gut axis for acute ischemic stroke and its effect on levels of IL-17, hs-CRP and TMAO[J]. Chinese Acupuncture and Moxibustion, 2022, 42(8): 853-856. DOI： 10.13703/j.0255-2930.20210821-k0004.

摘要

目的：比较“脑肠同调”法针刺与常规针刺治疗急性脑梗死的临床疗效，并探讨其作用机制。方法：将64例急性脑梗死患者随机分为观察组和对照组，每组32例。两组均采用西医基础治疗，观察组予“脑肠同调”法针刺治疗，穴取顶颞前斜线、中脘、关元、天枢、足三里、上巨虚、下巨虚；对照组予常规针刺治疗，均每日1次，每周治疗6 d，共治疗3周。比较两组患者治疗前后美国国立卫生院卒中量表（NIHSS）评分，血清白细胞介素17(IL-17)、超敏C反应蛋白（hs-CRP）水平，及血浆氧化三甲胺（TMAO）水平。结果：治疗后，两组患者NIHSS评分，血清IL-17、hs-CRP水平，血浆TMAO水平均较治疗前降低（P<0.01），且观察组低于对照组（P<0.05）。结论：“脑肠同调”法针刺可改善急性脑梗死患者神经功能，疗效优于常规针刺。其机制可能与调节炎性反应及肠道菌群代谢产物水平有关。

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