<italic style="font-style: italic">Hunyuan</italic> moxibustion for diarrhea-predominant irritable bowel syndrome of spleen and kidney <italic style="font-style: italic">yang</italic> deficiency: a randomized controlled trial

GENG Le-le; HUANG Hui; XUAN Yi-chen; WAN Ji-wei; YU Xi-jing; NIE Xiao-feng; HU Xiu-wu

doi:10.13703/j.0255-2930.20220219-k0001

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Hunyuan moxibustion for diarrhea-predominant irritable bowel syndrome of spleen and kidney yang deficiency: a randomized controlled trial

Clinical Research | 更新时间：2024-06-03

- Hunyuan moxibustion for diarrhea-predominant irritable bowel syndrome of spleen and kidney yang deficiency: a randomized controlled trial
- Chinese Acupuncture & Moxibustion Vol. 43, Issue 9, Pages: 1028-1032(2023)
- 作者机构：
  
  1.南昌市洪都中医院针灸科，江西南昌330006
  2.江西省针灸医学临床研究中心，南昌330006
  3.南昌市长蛇灸效应机制和督脉特异性重点实验室，江西南昌330006
  4.南昌医学院中医学院
- 作者简介：
- 基金信息：
- DOI：10.13703/j.0255-2930.20220219-k0001
  CLC： R 246.1
- Received：19 February 2022，
  
  Online First：04 November 2022，
  
  Published：12 September 2023
- 稿件说明：
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耿乐乐,黄辉,宣逸尘等.混元灸治疗脾肾阳虚证腹泻型肠易激综合征：随机对照试验[J].中国针灸,2023,43(09):1028-1032.

GENG Le-le,HUANG Hui,XUAN Yi-chen,et al.Hunyuan moxibustion for diarrhea-predominant irritable bowel syndrome of spleen and kidney yang deficiency: a randomized controlled trial[J].Chinese Acupuncture & Moxibustion,2023,43(09):1028-1032.
耿乐乐,黄辉,宣逸尘等.混元灸治疗脾肾阳虚证腹泻型肠易激综合征：随机对照试验[J].中国针灸,2023,43(09):1028-1032. DOI： 10.13703/j.0255-2930.20220219-k0001.

GENG Le-le,HUANG Hui,XUAN Yi-chen,et al.Hunyuan moxibustion for diarrhea-predominant irritable bowel syndrome of spleen and kidney yang deficiency: a randomized controlled trial[J].Chinese Acupuncture & Moxibustion,2023,43(09):1028-1032. DOI： 10.13703/j.0255-2930.20220219-k0001.

摘要

目的

比较混元灸与口服西药治疗脾肾阳虚证腹泻型肠易激综合征（IBS-D）的临床疗效。

方法

将60例脾肾阳虚证IBS-D患者随机分为混元灸组和西药组，每组30例。混元灸组予关元穴混元灸治疗，每次约40 min，每天1次；西药组予口服盐酸洛哌丁胺胶囊（2 mg/次，每天3次）和地衣芽孢杆菌活菌胶囊（0.5 g/次，每天3次）。两组均治疗20 d，观察两组患者治疗前后IBS病情严重程度量表（IBS-SSS）评分、IBS生活质量量表（IBS-QOL）评分及中医症状分级量化评分，并评定两组临床疗效及安全性。

结果

治疗后，两组患者IBS-SSS各项评分及总评分均低于治疗前、IBS-QOL总评分均高于治疗前（

0.05），混元灸组IBS-SSS各项评分及总评分均低于西药组、IBS-QOL总评分高于西药组（

0.05）。治疗后，混元灸组中医症状分级量化各项评分及总评分均低于治疗前（

0.05），西药组腹痛、腹泻、不思饮食及总评分均低于治疗前（

0.05）；混元灸组腹痛、腰膝酸软、畏寒肢冷及总评分均低于西药组（

0.05）。混元灸组总有效率高于西药组［90.0%（27/30）

73.3%（22/30），

0.05］。治疗期间两组患者均未出现不良反应。

结论

混元灸可有效改善脾肾阳虚证IBS-D患者病情严重程度，提高患者生活质量，尤其在改善腹痛、腰膝酸软和畏寒肢冷症状及总体疗效方面优于口服西药。

Abstract

Objective

To compare the therapeutic effect between

Hunyuan

moxibustion and oral western medication on diarrhea-predominant irritable bowel syndrome（IBS-D）of spleen and kidney

yang

deficiency.

Methods

Sixty patients with IBS

-D of spleen and kidney

yang

deficiency were randomly divided into a Hunyuan moxibustion group and a western medication group

30 cases each group. The Hunyuan moxibustion group was treated with

Hunyuan

moxibustion at Guanyuan（CV 4），40 min each time

once a day; in the western medication group，loperamide hydrochloride capsules (2 mg each time

3 times a day) and bacillus licheniformis live capsules (0.5 g each time

3 times a day) were given orally.Both groups were treated for 20 days. The scores of irritable bowel syndrome（IBS）symptom severity scale（IBS-SSS）

IBS quality of life scale (IBS-QOL) and TCM symptom grading quantitative were observed before and after treatment

and the clinical efficacy and safety were evaluated in the two groups.

Results

After treatment，each item scores and total scores of IBS-SSS in the two groups were lower than those before treatment（

0.05）

and the total scores of IBS-QOL were higher than those before treatment (

0.05)；each item score and total score of IBS-SSS in the Hunyuan moxibustion group were lower than those in the western medication group (

0.05)

and the total score of IBS-QOL in the Hunyuan moxibustion group was higher than that in the western medication group (

0.05).After treatment

each item score and total score of TCM symptom grading quantitative in the Hunyuan moxibustion group were lower than those before treatment (

0.05)

the abdominal pain

diarrhea

lack of appetite scores and total score in the western medication group were lower than those before treatment (

0.05)；and the abdominal pain

soreness and weakness of waist and knees

fear to cold and cold limbs scores and total score in the Hunyuan moxibustion group were lower than those in the western medication group (

0.05).The total effective rate was 90.0%（27/30）in the Hunyuan moxibustion group

whi

ch was higher than 73.3%（22/30）in the western medication group (

0.05). No adverse reactions occurred in both groups during treatment.

Conclusion

Hunyuan

moxibustion can effectively improve the symptom severity and quality of life in patients with IBS-D of spleen and kidney

yang

deficiency

especially in improving the symptoms of abdominal pain

soreness and weakness of waist and knees

fear to cold and cold limbs.Its therapeutic effect is superior to western medication.

关键词

Keywords

references

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Hunyuan moxibustion for diarrhea-predominant irritable bowel syndrome of spleen and kidney yang deficiency: a randomized controlled trial

DOI：10.13703/j.0255-2930.20220219-k0001

摘要

Abstract

关键词

Keywords

references