Combination of acupuncture and medication for dry eye complicated with computer vision syndrome: a randomized controlled trial

ZHAO Lei; DONG Bao-qiang; ZUO Tao; ZHANG Zhu-qiang; WANG Fang-yuan; ZHOU Hui-min

doi:10.13703/j.0255-2930.20221009-0001

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Combination of acupuncture and medication for dry eye complicated with computer vision syndrome: a randomized controlled trial

Clinical Research | 更新时间：2024-06-03

- Combination of acupuncture and medication for dry eye complicated with computer vision syndrome: a randomized controlled trial
- Chinese Acupuncture & Moxibustion Vol. 43, Issue 10, Pages: 1134-1138(2023)
- 作者机构：
  
  1.辽宁中医药大学针灸推拿学院，沈阳 110032
  2.辽宁中医药大学附属第二医院眼科
- 作者简介：
- 基金信息：
- DOI：10.13703/j.0255-2930.20221009-0001
  CLC： R 246.82
- Received：09 October 2022，
  
  Online First：27 July 2023，
  
  Published：12 October 2023
- 稿件说明：
移动端阅览
赵磊,董宝强,左韬等.针药结合治疗干眼合并视频终端综合征：随机对照试验[J].中国针灸,2023,43(10):1134-1138.

ZHAO Lei,DONG Bao-qiang,ZUO Tao,et al.Combination of acupuncture and medication for dry eye complicated with computer vision syndrome: a randomized controlled trial[J].Chinese Acupuncture & Moxibustion,2023,43(10):1134-1138.
赵磊,董宝强,左韬等.针药结合治疗干眼合并视频终端综合征：随机对照试验[J].中国针灸,2023,43(10):1134-1138. DOI： 10.13703/j.0255-2930.20221009-0001.

ZHAO Lei,DONG Bao-qiang,ZUO Tao,et al.Combination of acupuncture and medication for dry eye complicated with computer vision syndrome: a randomized controlled trial[J].Chinese Acupuncture & Moxibustion,2023,43(10):1134-1138. DOI： 10.13703/j.0255-2930.20221009-0001.

摘要

目的

比较针刺、中药及针药结合治疗干眼合并视频终端综合征（CVS）的临床疗效。

方法

将152例干眼合并CVS患者随机分为针药组（38例，剔除1例）、针刺组（38例，脱落1例）、中药组（38例，剔除1例）和西药组（38例，脱落1例）。西药组予玻璃酸钠滴眼液联合七叶洋地黄双苷滴眼液治疗；针刺组针刺双侧太阳、攒竹、风池、期门、合谷等，每日1次；中药组口服益气聪明汤配方颗粒，每日1剂；针药组予针刺结合益气聪明汤配方颗粒治疗。均治疗14 d。比较各组患者治疗前后非侵犯性第1次泪膜破裂时间（NIBUT f）、非侵犯性平均泪膜破裂时间（NIBUT av）、泪河高度（TMH）、眼表疾病症状指数（OSDI）评分及CVS症状积分。

结果

治疗后，4组患者NIBUT f、NIBUT av、TMH均较治疗前升高（

0.01）；针药组、针刺组NIBUT f、NIBUT av高于中药组、西药组（

0.05），针药组、中药组TMH高于针刺组、西药组（

0.05）。治疗后，4组患者OSDI评分、CVS各项积分及总分（除西药组头部症状积分外）均较治疗前降低（

0.01）；针药组OSDI评分及CVS总分、眼部症状积分、躯体症状积分低于针刺组、中药组、西药组（

0.01，

0.05），针药组头部症状积分低于西药组（

0.05），针药组、针刺组CVS躯体症状积分、精神认知症状积分低于中药组、西药组（

0.05）。

结论

针刺疗法在改善NIBUT f、NIBUT av及CVS躯体症状、精神认知症状方面具有优势，中药在改善TMH方面具有优势，针药结合相较于单一疗法效果更佳。

Abstract

Objective

To compare the clinical efficacy of acupuncture

Chinese medication and combination of acupuncture and medication in the treatment of dry eye complicated with computer vision syndrome (CVS).

Methods

A total of 152 patients with dry eye complicated with CVS were randomly divided into an acupuncture-medication group (38 cases

1 case was removed)

an acupuncture group (38 cases

1 case dropped off)

a Chinese medication group (38 cases

1 case was removed)

and a western medication group (38 cases

1 case dropped off). In the western medication group

sodium hyaluronate eye drop combined with esculin and digitalis glycosides eye drop were used. In the acupuncture group

acupuncture was applied at bilateral Taiyang (EX-HN 5)， Cuanzhu (BL 2)

Fengchi (GB 20)

Qime

n (LR 14)

and Hegu (LI 4) etc.

once a day. In the Chinese medication group

Yiqi Congming

decoction formula ganule was given orally

one dose a day. In the acupuncture-medication group

acupuncture combined with

Yiqi Congming

decoction formula granule were used. All groups were treated for 14 d. The non-invasive first tear film break-up time (NIBUT f)

non-invasive average tear film break-up time (NIBUT av)

tear meniscus height (TMH)

ocular surface disease index (OSDI) score

and CVS symptom score were compared between the patients of each group before and after treatment.

Results

After treatment

the NIBUT f

NIBUT av

and TMH were increased compared with those before treatment in the patients of the 4 groups (

0.01); the NIBUT f and NIBUT av in the acupuncture-medication group and the acupuncture group were higher than those in the Chinese medication group and the western medication group (

0.05)

and the TMH in the acupuncture-medication group and the Chinese medication group were higher than those in the acupuncture group and the western medication group (

0.05). After treatment

the OSDI scores

the various scores and total scores of CVS (except for head symptom score in the western medication group) were decreased compared with those before treatment in the patients of the 4 groups (

0.01). The OSDI score

total score

eye symptom score

and body symptom score of CVS in the acupuncture-medication group were lower than those in the acupuncture group

the Chinese medication group

and the western medication group (

0.01

0.05)

the head symptom score of the acupuncture-medication group was lower than that in the western medication group (

0.05)

and the CVS physical symptom scores and mental cognitive symptom scores of the acupuncture-medication group and the acupuncture group were lower than t

hose in the Chinese medication group and the western medication group (

0.05).

Conclusion

Acupuncture has advantages in improving NIBUT f

NIBUT av

and CVS physical symptoms and cognitive symptoms

and the Chinese medication has advantage in improving TMH. The combination of acupuncture and Chinese medication has better effects compared with monotherapy.

关键词

Keywords

references

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