To compare the clinical efficacy and safety of acupuncture and sodium hyaluronate eye drop in the treatment of aqueous deficiency dry eye.
Methods
2
A total of 60 patients (120 eyes) with aqueous deficiency dry eye were randomly divided into an observation group (30 cases
1 case dropped out) and a control group (30 cases
1 case dropped out). In the control group
sodium hyaluronate eye drop were used
one drop at a time
4 times a day
for 14 consecutive days. In the observation group
acupuncture was applied at bilateral Shangjingming (Extra)
Cuanzhu (BL 2)
Sizhukong (TE 23)
Taiyang (EX-HN 5)
and Tongziliao (GB 1)
once a day
treatment for 6 days with the interval of 1 day was required
for 14 consecutive days. The tear meniscus height (TMH)
Schirmer Ⅰ test (SⅠT)
ocular surface disease index (OSDI) score
non-invasive tear break-up time (NIBUT)
and corneal fluorescein sodium staining (FLS) score were compared between the two groups before and after treatment
and the safety of the treatment of the two groups was observed.
Results
2
Compared with those before treatment
after treatment
TMH
SⅠT and NIBUT were increased (
P
<
0.01
P
<
0.05)
and FLS scores were decreased (
P
<
0.01) in the two groups; the score of OSDI was reduced (
P
<
0.01) in the observation group. After treatment
in the observation group
TMH and SⅠT were higher than those in the control group (
P
<
0.01)
and the score of OSDI was lower than that in the control group (
P
<
0.01). No adverse reactions and adverse events were observed in the two groups.
Conclusion
2
Acupuncture and sodium hyaluronate eye drop can both effectively treat aqueous deficiency dry eye
acupuncture has obvious advantages in improving TMH and basic tear secretion
and reducing the subjective symptoms of patients. Acupuncture for dry eye is safe.
关键词
Keywords
references
Tsubota K , Yokoi N , Watanabe H , et al . A new perspective on dry eye classification: proposal by the Asia dry eye society [J ] . Eye Contact Lens , 2020 , 46 Suppl( 1 ): S2 - S13 .
Zhang X , Zhang B , Peng SY , et al . Effectiveness of acupuncture at acupoint BL1 (Jingming) in comparison with artificial tears for moderate to severe dry eye disease: a randomized controlled trial [J ] . Trials , 2022 , 23 ( 1 ): 605 .
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Related Author
XU Xinyi
XIAO Lu
GAO Ying
MIAO Changhong
SHAN Ziqi
ZHANG Yifang
WANG Yuanchong
YANG Xiaokun
Related Institution
Department of Emergency, First Teaching Hospital of Tianjin University of TCM
Department of Education, First Teaching Hospital of Tianjin University of TCM
National Clinical Research Center for Traditional Chinese Medicine
Department of Pediatrics, Beijing Hospital of TCM, Capital Medical University
Department of Acupuncture and Moxibustion, Beijing Hospital of TCM, Capital Medical University