Heat-sensitive moxibustion combined with <italic style="font-style: italic">Xiangwu</italic> powder for erectile dysfunction with kidney deficiency and blood stasis: a randomized controlled trial

GAO Wuzhi; SUN Zixue; CHEN Xiang; LI Pengchao; ZHANG Xinghua; CHEN Jianshe; GENG Liyan; ZHANG Chenming

doi:10.13703/j.0255-2930.20230409-0004

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Heat-sensitive moxibustion combined with Xiangwu powder for erectile dysfunction with kidney deficiency and blood stasis: a randomized controlled trial

Clinical Research | 更新时间：2024-06-03

- Heat-sensitive moxibustion combined with Xiangwu powder for erectile dysfunction with kidney deficiency and blood stasis: a randomized controlled trial
- Chinese Acupuncture & Moxibustion Vol. 44, Issue 2, Pages: 144-148(2024)
- 作者机构：
  
  河南省中医院/河南中医药大学第二附属医院生殖医学科，郑州 450002
- 作者简介：
- 基金信息：
- DOI：10.13703/j.0255-2930.20230409-0004
  CLC：
- Received：09 April 2023，
  
  Online First：00 December 2023，
  
  Published：12 February 2024
- 稿件说明：
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高五芝,孙自学,陈翔等.热敏灸联合香蜈散治疗肾虚血瘀型勃起功能障碍：随机对照试验[J].中国针灸,2024,44(02):144-148.

GAO Wuzhi,SUN Zixue,CHEN Xiang,et al.Heat-sensitive moxibustion combined with Xiangwu powder for erectile dysfunction with kidney deficiency and blood stasis: a randomized controlled trial[J].Chinese Acupuncture & Moxibustion,2024,44(02):144-148.
高五芝,孙自学,陈翔等.热敏灸联合香蜈散治疗肾虚血瘀型勃起功能障碍：随机对照试验[J].中国针灸,2024,44(02):144-148. DOI： 10.13703/j.0255-2930.20230409-0004.

GAO Wuzhi,SUN Zixue,CHEN Xiang,et al.Heat-sensitive moxibustion combined with Xiangwu powder for erectile dysfunction with kidney deficiency and blood stasis: a randomized controlled trial[J].Chinese Acupuncture & Moxibustion,2024,44(02):144-148. DOI： 10.13703/j.0255-2930.20230409-0004.

摘要

目的

观察热敏灸联合香蜈散治疗肾虚血瘀型勃起功能障碍的临床疗效。

方法

将80例肾虚血瘀型勃起功能障碍患者随机分为综合组（40例，脱落1例）和中药组（40例，脱落2例）。中药组口服香蜈散治疗，每日1剂，治疗4周；综合组在中药组基础上于关元、中极、气海及双侧血海、三阴交穴区探寻热敏腧穴行热敏灸治疗，每日1次，每周5次，治疗4周。分别于治疗前后观察两组患者勃起功能国际问卷-5（IIEF-5）评分、勃起硬度评分（EHS）、夜间阴茎勃起硬度监测（NPTR）指标［夜间阴茎勃起次数、阴茎勃起总持续时间、阴茎头部硬度≥60%持续时间、阴茎根部硬度≥60% 持续时间、阴茎头部周径变化百分比、阴茎根部周径变化百分比］、中医证候积分、阴茎血管功能指标［阴茎海绵体动脉收缩期峰值流速（PSV）、舒张末期流速（EDV）、阻力指数（RI）］，并评定两组临床疗效。

结果

治疗后，两组患者IIEF-5评分、EHS、PSV、RI及NPTR指标均较治疗前升高（

0.01），中医证候积分及EDV均较治疗前降低（

0.01）；综合组患者IIEF-5评分、EHS、PSV、RI及NPTR指标均高于中药组（

0.01），中医证候积分及EDV均低于中药组（

0.01）。综合组总有效率为94.9%（37/39），高于中药组的78.9%（30/38，

0.05）。

结论

热敏灸联合香蜈散可有效治疗肾虚血瘀型勃起功能障碍，改善患者勃起功能，提高其勃起硬度，改善其阴茎血管功能与临床症状。

Abstract

Objective

To observe the clinical efficacy of heat-sensitive moxibustion combined with

Xiangwu

powder in treating erectile dysfunction with kidney deficiency and blood stasis.

Methods

A total of 80 patients with erectile dysfunction of kidney deficiency and blood stasis were randomly divided into a comprehensive group (40 cases

1 case dropped out) and a Chinese herb group (40 cases

2 cases dropped out). In the Chinese herb group

Xiangwu

powder was applied orally

one dose per day. On the basis of the Chinese herb group

heat-sensitive moxibustio

n was applied after detecting the heat-sensitive points in the areas of Guanyuan (CV 4)

Zhongji (CV 3)

Qihai (CV 6) and bilateral Xuehai (SP 10)

Sanyinjiao (SP 6) in the comprehensive group

once a day

5 times a week. Both groups were treated for 4 weeks. The international index of erectile function-5 (IIEF-5) score

erectile hardness score (EHS)

nocturnal penile tumescence and rigidity (NPTR) indexes (nocturnal penile erection frequency

total duration of penile erection

duration of penile head hardness ≥60%

duration of penile root hardness ≥60%

percentage change in penile head circumference

percentage change in penile root circumference)

TCM syndrome score

and penile vascular function indexes (peak systolic velocity [PSV

]

end diastolic velocity [EDV

]

and resistance index [RI

]

of penile cavernosal artery) were compared in the patients of the two groups before and after treatment

and the clinical efficacy was evaluated.

Results

After treatment

the IIEF-5 scores

EHS

PSV

and NPTR indexes were increased compared with those before treatment (

0.01)

while the TCM syndrome scores and EDV were decreased compared with those before treatment (

0.01) in the two groups.The IIEF-5 score

EHS

PSV

and NPTR indexes in the comprehensive group were ascended compared with those in the Chinese herb group (

0.01)

while the TCM syndrome score and EDV in the comprehensive group were lower than those in the traditional Chinese herb group (

0.01). The total effective rate of the comprehensive group was 94.9% (37/39)

which was higher than 78.9% (30/38

0.05) of the Chinese herb group.

Conclusion

The combination of heat-sensitive moxibustion and

Xiangwu

powder can effectively treat erectile dysfunction of kidney deficiency and blood stasis

improve patients' erectile function

enhance their erection hardness

and improve their

penile vascular function and clinical symptoms.

关键词

Keywords

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Heat-sensitive moxibustion combined with Xiangwu powder for erectile dysfunction with kidney deficiency and blood stasis: a randomized controlled trial

DOI：10.13703/j.0255-2930.20230409-0004

摘要

Abstract

关键词

Keywords

references