Research progression of acupuncture-moxibustion in treatment of rheumatoid arthritis

LIN Ying; SHEN Chuchu; XU Senlei; BAI Hua; CHEN Jing; YAN Rugen; ZHANG Hongru

doi:10.13703/j.0255-2930.20240222-0003

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Research progression of acupuncture-moxibustion in treatment of rheumatoid arthritis

Review | 更新时间：2024-12-12

- Research progression of acupuncture-moxibustion in treatment of rheumatoid arthritis
- Chinese Acupuncture & Moxibustion Vol. 44, Issue 12, Pages: 1479-1488(2024)
- 作者机构：
  
  1.南京中医药大学中西医结合学院，江苏　南京　210023
  2.南京中医药大学针灸推拿学院·养生康复学院，江苏　南京　210023
  3.南京中医药大学医学院，江苏　南京　210023
- 作者简介：
- 基金信息：
- DOI：10.13703/j.0255-2930.20240222-0003
  CLC：
- Received：22 February 2024，
  
  Online First：24 September 2024，
  
  Published：12 December 2024
- 稿件说明：
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LIN Ying, SHEN Chuchu, XU Senlei, et al. Research progression of acupuncture-moxibustion in treatment of rheumatoid arthritis[J]. Chinese Acupuncture & Moxibustion, 2024, 44(12): 1479-1488.
DOI：

LIN Ying, SHEN Chuchu, XU Senlei, et al. Research progression of acupuncture-moxibustion in treatment of rheumatoid arthritis[J]. Chinese Acupuncture & Moxibustion, 2024, 44(12): 1479-1488. DOI： 10.13703/j.0255-2930.20240222-0003.

摘要

本文对近20余年针灸治疗类风湿关节炎（RA）的国内外临床研究和机制研究进行梳理。结果表明，针灸治疗可以使RA患者获益且不良反应较少，在一定程度上改善RA患者的关节功能和生活质量。针灸治疗RA是多靶点、多层次共同作用的结果，针灸疗效机制包括从整体角度上调节神经-免疫-内分泌系统，以及通过抑制炎性反应、调节相关信号通路、维持骨细胞和关节软骨内平衡、调节基因表达等改善RA。尽管针灸治疗RA的临床和机制研究已取得一定进展，但针灸治疗RA的机制仍有待深入探索，从而推动针灸疗法在临床上的广泛应用，为其创新和发展提供新的思路。

Abstract

The article reviews the clinical and mechanism researches of acupuncture-moxibustion in treatment of rheumatoid arthritis (RA) in recent two decades at home and abroad. The results indicate that acupuncture-moxibustion is conductive to RA with fewer adverse reactions for the patients

and improves joint function and quality of life to a certain extent. The therapeutic results of acupuncture-moxibustion result from the multi-target

multi-level collaborative effect on RA. In mechanism

the overall regulation of the neuro-immuno-endocrine system is involved. RA is attenuated through inhibiting inflammatory responses

regulating relevant signaling pathways

maintaining the balance of osteoblasts and articular cartilage

and adjusting the gene expression. Although some achievements have been obtained in clinical and mechanism researches

it still needs to deepen the mechanism research so as to promote the clinical application of acupuncture-moxibustion and provide the new approaches to its innovation and development.

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