TAO Lamei, LI Jing, LU Jin, et al. Fuʹs subcutaneous needling for non-acute idiopathic facial paralysis : a randomized controlled trial[J]. Chinese Acupuncture & Moxibustion, 2024, 44(11): 1249-1253. DOI: 10.13703/j.0255-2930.20240611-k0001.
DOI:
TAO Lamei, LI Jing, LU Jin, et al. Fuʹs subcutaneous needling for non-acute idiopathic facial paralysis : a randomized controlled trial[J]. Chinese Acupuncture & Moxibustion, 2024, 44(11): 1249-1253. DOI: 10.13703/j.0255-2930.20240611-k0001.DOI:
Fuʹs subcutaneous needling for non-acute idiopathic facial paralysis : a randomized controlled trial
's subcutaneous needling in the treatment of non-acute idiopathic facial paralysis and its effect on serum levels of nitric oxide (NO) and endothelin (ET).
Methods
2
A total of 76 patients with non-acute idiopathic facial paralysis were randomly divided into an observation group (38 cases
2 cases dropped out) and a control group (38 cases
2 cases dropped out). The patients in the control group received basic treatment (mecobalamin tablets orally
specific electromagnetic spectrum irradiation
facial muscle rehabilitation training). The patients in the observation group were treated with
Fu
's subcutaneous needling on the basis of the control group. The needling points included brachioradialis muscle
sternocleidomastoid muscle
trapezius muscle
etc.
and the needling was inserted around the affected muscle
and the reperfusion activity was carried out at the same time
once every other day
3 times a week. Both groups were treated for 4 weeks. The House-Brackmann (H-B) grade and H-B symptom score were observed before treatment
after 2 and 4 weeks of treatment in the two groups. The facial disability index (FDI) score [including physical function (FDIP) score and social life function (FDIS) score
]
and the serum levels of NO and ET were compared before and after 4 weeks of treatment in the two groups. The clinical effect and safety of the two groups were assessed.
Results
2
After 2 and 4 weeks of treatment
the H-B grade of the two groups was lower than that before treatment
and the H-B symptom scores were higher than those before treatment (
P
<
0.001
P
<
0.05); the H-B grade of the observation group was lower than that of the control group
and the H-B symptom score was higher than that of the control group (
P
<
0.01
P
<
0.05). After 4 weeks of treatment
the FDIP scores of the two groups were higher than those before treatment
and the FDIS scores were lower than those before treatment (
P
<
0.05 ); the FDIP score of the observation group was higher than that of the control group
and the FDIS score was lower than that of the control group (
P
<
0.05). After 4 weeks of treatment
the serum level of NO in the observation group was higher than that before treatment
and the serum level of ET was lower than that before treatment (
P
<
0.05); the increase of serum level of NO and the decrease of serum level of ET in the observation group were greater than those in the control group (
P
<
0.05). The cure rate of th
e observation group was 55.6% (20/36)
which was higher than 22.2% (8/36) of the control group (
P
<
0.05). There were no serious adverse reactions in both groups.
Conclusion
2
Fu
's subcutaneous needling combined with basic treatment can effectively improve the motor function of facial muscles in patients with non-acute idiopathic facial paralysis
which may be related to the regulation of serum NO and ET levels.
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Related Author
GONG Meng
LIU Zhixiang
LI Pei
XIAO Renyan
JIA Peng
GUO Hong
JIN Song
WANG Lili
Related Institution
School of Acupuncture-Moxibustion and Tuina, Chengdu University of TCM
School of Health Preservation and Rehabilitation, Chengdu University of TCM
Department of Rehabilitation, Affiliated Hospital of Chengdu University of TCM
Graduate School, Heilongjiang University of CM
Second Department of Neurorehabilitation, Second Affiliated Hospital of Heilongjiang University of CM