Efficacy of eye transcutaneous electrical acupoint stimulation on preventing the progression of pre-myopic to myopia in children

LOU Qian; XU Furu; JIANG Wenjun; QU Yi; SUN Longjiao; BI Hongsheng

doi:10.13703/j.0255-2930.20240808-k0001

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Efficacy of eye transcutaneous electrical acupoint stimulation on preventing the progression of pre-myopic to myopia in children

Clinical Research | 更新时间：2025-02-14

- Efficacy of eye transcutaneous electrical acupoint stimulation on preventing the progression of pre-myopic to myopia in children
- Chinese Acupuncture & Moxibustion Vol. 45, Issue 2, Pages: 173-178(2025)
- 作者机构：
  
  1.山东中医药大学眼科与视光医学院，济南　250014
  2.山东中医药大学附属眼科医院，济南　250002
  3.山东省中西医结合眼病防治重点实验室/山东省眼病防治研究院，济南　250002
- 作者简介：
- 基金信息：
- DOI：10.13703/j.0255-2930.20240808-k0001
  CLC：
- Received：08 August 2024，
  
  Online First：28 November 2024，
  
  Published：12 February 2025
- 稿件说明：
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LOU Qian, XU Furu, JIANG Wenjun, et al. Efficacy of eye transcutaneous electrical acupoint stimulation on preventing the progression of pre-myopic to myopia in children[J]. Chinese Acupuncture & Moxibustion, 2025, 45(2): 173-178.
DOI：

LOU Qian, XU Furu, JIANG Wenjun, et al. Efficacy of eye transcutaneous electrical acupoint stimulation on preventing the progression of pre-myopic to myopia in children[J]. Chinese Acupuncture & Moxibustion, 2025, 45(2): 173-178. DOI： 10.13703/j.0255-2930.20240808-k0001.

摘要

目的：

观察眼周经皮穴位电刺激（Eye-TEAS）预防6~12岁儿童近视临床前期向近视进展的疗效及安全性。

方法：

将170例6~12岁近视临床前期儿童随机分为TEAS组（85例，脱落3例，剔除2例）和假TEAS组（85例，脱落3例，剔除2例）。TEAS组接受Eye-TEAS干预，穴取双侧攒竹、鱼腰、丝竹空、太阳、四白、睛明，予连续波，频率4 Hz，电流1~2 mA，每次刺激30 min；假TEAS组接受假Eye-TEAS干预，仪器外观、操作方法和取穴部位相同，但无电刺激。两组均隔日1次，每周至少3次，持续治疗20周。于干预后、干预结束后28周随访，比较两组受试儿童眼轴长度（AL）、等效球镜度（SER）的变化量及近视发生率，评价干预期间依从性和安全性。

结果：

干预后、随访时，两组受试儿童AL高于干预前（

0.01）；随访时，两组受试儿童AL高于干预后（

0.01）。干预后、随访时，TEAS组受试儿童AL变化量均低于假TEAS组（

0.01，

0.05）。干预后、随访时，两组受试儿童SER低于干预前（

0.01）；随访时，两组受试儿童SER低于干预后（

0.01）。干预后，TEAS组受试儿童SER高于假TEAS组（

0.05）；干预后、随访时，TEAS组受试儿童SER变化量低于假TEAS组（

0.01）。随访时，TEAS组近视发生率低于假TEAS组[20.0%（14/70）

34.7%（25/72），

0.05

]

。两组均依从性良好，未出现与治疗相关的不良事件。

结论：

Eye-TEAS能够延缓儿童近视临床前期向近视进展，安全性较高。

Abstract

Objective

To observe the efficacy and safety of eye transcutaneous electrical acupoint stimulation (Eye-TEAS) on preventing the progression of pre-myopic to myopia in children aged 6-12 years.

Methods

A total of 170 pre-myopic children aged 6-12 years were randomly divided into an Eye-TEAS group (85 cases

3 cases dropped out

2 cases were eliminated) and a placebo Eye-TEAS group (85 cases

3 cases dropped out

2 cases were eliminated). The Eye-TEAS group received Eye-TEAS intervention at bilateral Cuanzhu (BL2)

Yuyao (EX-HN4)

Sizhukong (TE23)

Taiyang (EX-HN5)

Sibai (ST2)

and Jingming (BL1)

with continuous wave at a frequency of 4 Hz and a current of 1-2 mA for 30 min per session. The placebo Eye-TEAS group received sham intervention with the same equipment and procedure

but no electrical stimulation. Both groups received intervention once every other day

at least 3 times a week

for a duration of 20 weeks. After intervention and during the 28-week follow-up period after the intervention completion

the changes in axial length (AL)

spherical equivalent refraction (SER)

and the incidence of myopia were compared between the two groups. Adherence and safety during the intervention period were also evaluated.

Results

Compared before intervention

both groups showed an increase in AL after the intervention and during the follow-up (

0.01). The AL during follow-up was higher than that after the intervention in the two groups (

0.01). The Eye-TEAS group exhibited a smaller change in AL than the placebo Eye-TEAS group after the intervention and during follow-up (

0.01

0.05). Compared before intervention

both groups showed a decrease in SER after the intervention and during follow-up (

0.01). The SER during follow-up was lower than that after the intervention in the two groups (

0.01). The Eye-TEAS group had a higher SER than the placebo Eye-TEAS group after the intervention (

0.05). The Eye-TEAS group exhibited a smaller change in SER than the placebo Eye-TEAS group after the intervention and during follow-up (

0.01). The incidence of myopia in the Eye-TEAS group was lower than that in the placebo group during follow-up (20.0% [14/70

]

34.7% [25/72

]

0.05). Both groups had good adherence

with no adverse events related to the intervention.

Conclusion

Eye-TEAS can delay the progression of pre-myopic to myopia in children

and has a high safety profile.

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