Research progress of acupuncture for the prevention and treatment of Alzheimer's disease based on the "kidney-governor vessel-brain" axis

TAN Qian; DU Yanjun; YOU Min

doi:10.13703/j.0255-2930.20240822-0004

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Research progress of acupuncture for the prevention and treatment of Alzheimer's disease based on the "kidney-governor vessel-brain" axis

Meridian-Zangfu Relationship | 更新时间：2025-05-15

- Research progress of acupuncture for the prevention and treatment of Alzheimer's disease based on the "kidney-governor vessel-brain" axis
- Chinese Acupuncture & Moxibustion Vol. 45, Issue 5, Pages: 601-608(2025)
- 作者机构：
  
  湖北中医药大学针灸骨伤学院，武汉　430065
  湖北时珍实验室，武汉　430065
  湖北省中医院，武汉　430061
- 作者简介：
- 基金信息：
- DOI：10.13703/j.0255-2930.20240822-0004
  CLC：
- Received：22 August 2024，
  
  Online First：13 January 2025，
  
  Published：12 May 2025
- 稿件说明：
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TAN Qian, DU Yanjun, YOU Min. Research progress of acupuncture for the prevention and treatment of Alzheimer's disease based on the "kidney-governor vessel-brain" axis[J]. Chinese Acupuncture & Moxibustion, 2025, 45(5): 601-608.
DOI：

TAN Qian, DU Yanjun, YOU Min. Research progress of acupuncture for the prevention and treatment of Alzheimer's disease based on the "kidney-governor vessel-brain" axis[J]. Chinese Acupuncture & Moxibustion, 2025, 45(5): 601-608. DOI： 10.13703/j.0255-2930.20240822-0004.

摘要

基于“肾-督脉-脑”轴探讨针灸防治阿尔茨海默病（AD）的研究进展。根据中医学AD肾虚髓减、神机失用的基本病机，以及督脉联络肾和脑两脏的关系，提出“肾-督脉-脑”轴的概念。根据督脉的循行和生理功能，以及三者相生互济的关系分析“肾-督脉-脑”轴理论基础；从传统医学理论和现代生物学角度阐明AD与“肾-督脉-脑”轴的关系；结合“肾-督脉-脑”轴防治AD的临床和机制研究，认为“肾-督脉-脑”轴为未来AD的防治研究提供了有益的思路和参考。

Abstract

This paper explores the research progress of acupuncture for the prevention and treatment of Alzheimer's disease (AD) based on the "kidney-governor vessel-brain" axis. According to the fundamental pathogenesis of AD in traditional Chinese medicine (TCM)

which attributes to kidney deficiency

marrow depletion

and impaired mental faculties

as well as the governor vessel's connection between the kidney and brain

the concept of the "kidney-governor vessel-brain" axis is proposed. The theoretical basis of the "kidney-governor vessel-brain" axis is analyzed based on the meridian pathway and physiological functions of the governor vessel

as well as the interdependent and mutually reinforcing relationships among the kidney

governor vessel

and brain. The relationship between AD and the "kidney-governor vessel-brain" axis is elucidated from both traditional medical theories and modern biological perspectives. Integrating clinical and mechanistic research on AD prevention and treatment based on this axis

it is suggested that the "kidney-governor vessel-brain" axis provides valuable insights and references for future research on AD prevention and treatment.

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