Analysis of acupoint selection rules for acupuncture for autism spectrum disorder based on data mining technology

LIU Zhuocan; LI Na; CHEN Chao; ZHANG Zhenwei; CAO Yan’e

doi:10.13703/j.0255-2930.20240902-0003

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Analysis of acupoint selection rules for acupuncture for autism spectrum disorder based on data mining technology

Literature Research | 更新时间：2025-10-11

- Analysis of acupoint selection rules for acupuncture for autism spectrum disorder based on data mining technology
- Chinese Acupuncture & Moxibustion Vol. 45, Issue 10, Pages: 1496-1504(2025)
- 作者机构：
  
  河北中医药大学研究生学院，石家庄　050091
  河北省中医院康复科，石家庄　050011
  平山县中医院康复科
- 作者简介：
- 基金信息：
- DOI：10.13703/j.0255-2930.20240902-0003
  CLC：
- Received：02 September 2024，
  
  Online First：12 June 2025，
  
  Published：12 October 2025
- 稿件说明：
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LIU Zhuocan, LI Na, CHEN Chao, et al. Analysis of acupoint selection rules for acupuncture for autism spectrum disorder based on data mining technology[J]. Chinese Acupuncture & Moxibustion, 2025, 45(10): 1496-1504.
DOI：

LIU Zhuocan, LI Na, CHEN Chao, et al. Analysis of acupoint selection rules for acupuncture for autism spectrum disorder based on data mining technology[J]. Chinese Acupuncture & Moxibustion, 2025, 45(10): 1496-1504. DOI： 10.13703/j.0255-2930.20240902-0003.

摘要

目的：

基于数据挖掘技术分析针灸干预孤独症谱系障碍（ASD）的核心选穴及辨证配伍规律。

方法：

检索中国期刊全文数据库（CNKI）、万方数据知识服务平台（Wanfang）、维普资讯中文期刊服务平台（VIP）、PubMed、Web of Science中针灸治疗ASD的相关文献，根据纳入与排除标准，提取有效信息后建立处方数据库。对腧穴的频次、归经、分布部位、特定穴进行描述性分析；Origin软件绘制高频腧穴图；IBM SPSS Modeler 18.0软件Apriori 算法对处方中腧穴进行关联规则分析；IBM SPSS Statistics 26.0软件对高频腧穴进行聚类分析；Cytoscape 3.10.0软件实现高频证型与腧穴间关系的可视化处理。

结果：

纳入文献223篇，涉及处方452条，其中辨证取穴处方223条，腧穴共205个，总频次4 067次；腧穴使用频次前5位依次为百会、四神针、智三针、颞三针和内关；选穴多为靳三针、督脉、头针和足太阳膀胱经腧穴，头颈部和四肢腧穴占比较高，特定穴中五输穴、原穴和背俞穴使用频次较高；关联规则表明四神针-定神针-智三针-颞三针为核心穴组；前20位高频腧穴聚类分析分为4类，分别为通督醒脑组、健脾养心组、靳三针调神组和益肾填髓组；临床以肾精亏虚、心肝火旺、痰蒙心窍、心脾两虚、肝郁气滞5种证型为主。

结论：

针灸治疗ASD的核心腧穴处方是四神针、定神针、智三针、颞三针，重视调神治神，以多脏腑同调、调和气血，兼以畅气机、平衡阴阳为其治疗原则，临证可辨证配穴。

Abstract

Objective

To analyze the core acupoint selection rules and syndrome-based compatibility patterns of acupuncture for autism spectrum disorder (ASD) using data mining techniques.

Methods

Relevant literature of acupuncture for ASD was retrieved from CNKI

Wanfang

VIP

PubMed

and Web of Science. After applying inclusion and exclusion criteria

a prescription database was established based on the extracted effective data. Descriptive analysis was conducted on the frequency

meridian tropism

anatomical distribution

and specific point. High-frequency acupoints were visualized using Origin software. The Apriori algorithm in IBM SPSS Modeler 18.0 was used for association rule analysis of acupoint combinations. Cluster analysis of high-frequency acupoints was performed using IBM SPSS Statistics 26.0. The relationships between high-frequency syndromes and acupoints were visualized using Cytoscape 3.10.0.

Results

A total of 223 studies and 452 prescriptions were included

among which 223 were based on syndrome differentiation. A total of 205 acupoints were included with a cumulative frequency of 4 067. The top five most frequently used acupoints were Baihui (GV20)

Sishenzhen

Zhisanzhen

Niesanzhen

and Neiguan (PC6). Acupoints were primarily from

Jin

’s three-needle therapy

the governor vessel

scalp acupuncture

and the foot-

taiyang

bladder meridian

with a high proportion of acupoints located on the head and neck and the limbs. Among specific point

five-

shu

points

yuan

-source points

and back-

shu

points were most frequently used. Association rule analysis revealed that the core acupoint group was Sishenzhen-Dingshenzhen-Zhisanzhen-Niesanzhen. Cluster analysis divided the top 20 high-frequency acupoints into four categories: governor vessel activation and brain awakening group

spleen strengthening and heart nourishing group

Jin

’s three-needle spirit-regulating group

and kidney-reinforcing and marrow-filling group. Cli

nically

the main syndrome patterns were kidney essence deficiency

hyperactivity of heart and liver fire

phlegm obstructing the heart orifices

dual deficiency of heart and spleen

and liver

stagnation.

Conclusion

The core acupoint prescriptions of acupuncture for ASD are Sishenzhen

Dingshenzhen

Zhisanzhen

and Niesanzhen. The treatment emphasizes spirit regulation and mental tranquility

guided by the principles of harmonizing multiple

zang

organs

regulating

and blood

unblocking

movement

and balancing

yin

and

yang

. Syndrome-based acupoint compatibility is recommended in clinical practice.

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