Herbal cake-separated moxibustion at <italic style="font-style: italic">Baliao</italic> acupoints for erectile dysfunction with kidney deficiency and blood stasis: a randomized controlled trial

DU Junge; LI Pengchao; SUN Zixue

doi:10.13703/j.0255-2930.20240924-0001

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Herbal cake-separated moxibustion at Baliao acupoints for erectile dysfunction with kidney deficiency and blood stasis: a randomized controlled trial

Clinical Research | 更新时间：2025-10-11

- Herbal cake-separated moxibustion at Baliao acupoints for erectile dysfunction with kidney deficiency and blood stasis: a randomized controlled trial
- Chinese Acupuncture & Moxibustion Vol. 45, Issue 10, Pages: 1434-1439(2025)
- 作者机构：
  
  河南省中医院/河南中医药大学第二附属医院男科与生殖诊疗中心，郑州　450002
- 作者简介：
- 基金信息：
- DOI：10.13703/j.0255-2930.20240924-0001
  CLC：
- Received：24 September 2024，
  
  Online First：23 June 2025，
  
  Published：12 October 2025
- 稿件说明：
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DU Junge, LI Pengchao, SUN Zixue. Herbal cake-separated moxibustion at Baliao acupoints for erectile dysfunction with kidney deficiency and blood stasis: a randomized controlled trial[J]. Chinese Acupuncture & Moxibustion, 2025, 45(10): 1434-1439. DOI: 10.13703/j.0255-2930.20240924-0001.
DOI：

DU Junge, LI Pengchao, SUN Zixue. Herbal cake-separated moxibustion at Baliao acupoints for erectile dysfunction with kidney deficiency and blood stasis: a randomized controlled trial[J]. Chinese Acupuncture & Moxibustion, 2025, 45(10): 1434-1439. DOI: 10.13703/j.0255-2930.20240924-0001. DOI：

摘要

目的：

比较八髎穴隔药饼灸联合西药与单纯西药治疗肾虚血瘀型勃起功能障碍（ED）的临床疗效。

方法：

将108例ED患者随机分为综合组（54例，脱落2例）及西药组（54例，剔除1例，脱落2例）。西药组予他达拉非片口服，每次5 mg，每日1次；综合组在西药组基础上联合八髎穴隔药饼灸外治，每周施灸2次(周二、周五进行)。两组均治疗4周。于治疗前后观察两组勃起功能国际问卷-5（IIEF-5）评分、中医证候评分、勃起硬度（EHS）评分、血清性激素水平[卵泡刺激素（FSH）、黄体生成素（LH）、泌乳素（PRL）、睾酮（T）]、阴茎血流动力学指标[阴茎海绵体动脉收缩期峰值流速（PSV）、舒张末期流速（EDV）、阻力指数（RI）]，并评定安全性与临床疗效。

结果：

治疗后，两组患者IIEF-5评分、EHS评分、血清T含量、阴茎海绵体PSV及RI均较治疗前升高（

0.05），除RI外综合组以上指标均高于西药组（

0.05）。治疗后，两组患者中医证候评分、血清FSH与LH含量及EDV较治疗前降低（

0.05），综合组血清PRL含量较治疗前降低（

0.05），综合组以上指标均低于西药组（

0.05）。综合组总有效率为88.5%（46/52），优于西药组72.5%（37/51，

0.05）。两组患者治疗过程中均未出现明显不良反应。

结论：

八髎穴隔药饼灸联合西药治疗可以调节ED患者性激素水平，改善阴茎供血，提高勃起功能及勃起硬度，疗效优于单纯西药治疗。

Abstract

Objective

To compare the clinical efficacy of herbal cake-separated moxibustion at

Baliao

acupoints combined with western medication versus western medication alone in treating erectile dysfunction (ED) with kidney deficiency and blood stasis.

Methods

A total of 108 ED patients were randomly divided into a combination group (54 cases

2 cases dropped out) and a western medication group (54 cases

1 case was eliminated

2 cases dropped out). The western medication group received oral tadalafil tablets 5 mg a time

once daily. The combination group received additional herbal cake-separated moxibustion at

Baliao

acupoints (Shangliao [BL31

]

Ciliao [BL32

]

Zhongliao [BL33

]

Xialiao [BL34

]

) twice weekly (administered on Tuesdays and Fridays). Both groups were treated for 4 weeks. The 5-question international index of erectile function (IIEF-5) score

erectile hardness assessment (EHS) score

TCM syndrome score

serum sex hormone levels (follicle-stimulating hormone [FSH

]

luteinizing hormone [LH

]

prolactin [PRL

]

testosterone [T

]

)

penile hemodynamic parameters [peak systolic velocity (PSV) of penile cavernosal artery

end-diastolic velocity (EDV)

resistance index (RI)

]

were compared before and after treatment between the two groups

and the safety and clinical efficacy were evaluated.

Results

After treatment

the IIEF-5 scor

EHS scores

serum T levels

PSV and RI of penile cavernosal artery were increased compared with those before treatment in the two groups (

0.05). Except for RI

the combination group exhibited significantly higher improvements in the above indexes than those in the western medication group (

0.05). After treatment

the TCM syndrome scores

the serum FSH

LH levels

and EDV in the two groups and the serum PRL level in the combination group were decreased compared with those before treatment (

0.05)

while the above indexes in the combination group were lower than those in the western medication group (

0.05). The total effective rate of the combination group was 88.5% (46/52)

which was superior to 72.5% (37/51) in the western medication group (

0.05). No significant adverse reactions occurred in either group.

Conclusion

Herbal cake-separated moxibustion at

Baliao

acupoints combined with western medicine can regulate sex hormone levels

improve penile blood supply

enhance erectile function and hardness

and is superior to western medication alone

with no observed adverse reactions.

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Related Institution

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⁰

Herbal cake-separated moxibustion at Baliao acupoints for erectile dysfunction with kidney deficiency and blood stasis: a randomized controlled trial

DOI：10.13703/j.0255-2930.20240924-0001

摘要

Abstract

关键词

Keywords

references