Based on the meaning of

yizhi weishu

(the frequency of needling depending on the therapeutic effect)

its guiding role in the treatment of sinew-related diseases

and the connotations of "knowledge" and "quantity"

this article proposes that the theoretical connotation of "taking knowledge as quantity" is the guiding principle for the formulation and operation of acupuncture manipulation quantification. In clinical and scientific research settings

with "knowledge" and "quantity" as guiding principle

conducting studies and practices on the quantitative-effect relationships of "acupoint-effect" "technique-effect" "manifestation-effect" and "time-effect" could improve the precision of formulation and operation of acupuncture manipulation quantification. The theoretical connotation of "taking knowledge as quantity" not only guides the formulation of acupuncture manipulation quantification

which could enhance standardization

operability

and reproducibility of acupuncture trea

tment

but also emphasizes the bidirectional experience between doctor and patient

which embodies the characteristics of individualized

precise

and scientific diagnosis and treatment in Traditional Chinese Medicine

thereby helping to improve the clinical efficacy of acupuncture.