Combination therapy of wheat-grained sized cone moxibustion and point-to-point needle insertion with medical ozone injection for 31 cases of allergic rhinitis

HAN Dong; YIN Chunsheng; YANG Yuping

doi:10.13703/j.0255-2930.20241202-k0007

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Combination therapy of wheat-grained sized cone moxibustion and point-to-point needle insertion with medical ozone injection for 31 cases of allergic rhinitis

Clinical Research | 更新时间：2025-12-11

- Combination therapy of wheat-grained sized cone moxibustion and point-to-point needle insertion with medical ozone injection for 31 cases of allergic rhinitis
- Chinese Acupuncture & Moxibustion Vol. 45, Issue 12, Pages: 1739-1742(2025)
- 作者机构：
  
  潍坊市中医院针灸推拿科，山东潍坊　261000
- 作者简介：
- 基金信息：
- DOI：10.13703/j.0255-2930.20241202-k0007
  CLC：
- Received：02 December 2024，
  
  Online First：30 September 2025，
  
  Published：12 December 2025
- 稿件说明：
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HAN Dong, YIN Chunsheng, YANG Yuping. Combination therapy of wheat-grained sized cone moxibustion and point-to-point needle insertion with medical ozone injection for 31 cases of allergic rhinitis[J]. Chinese Acupuncture & Moxibustion, 2025, 45(12): 1739-1742.
DOI：

HAN Dong, YIN Chunsheng, YANG Yuping. Combination therapy of wheat-grained sized cone moxibustion and point-to-point needle insertion with medical ozone injection for 31 cases of allergic rhinitis[J]. Chinese Acupuncture & Moxibustion, 2025, 45(12): 1739-1742. DOI： 10.13703/j.0255-2930.20241202-k0007.

摘要

目的：

观察麦粒灸联合医用臭氧穴位透刺注射治疗变应性鼻炎（AR）的疗效，及其对炎症相关指标的影响。

方法：

纳入31例持续性AR患者，于迎香（双侧）、上迎香（双侧）进行医用臭氧透刺注射，于大椎行麦粒灸治疗，每周2次（隔3 d治疗1次），连续治疗4周。于治疗前、治疗后以及治疗结束后8周（随访），评价患者鼻部症状总分量表（TNSS）、鼻伴随症状积分量表（TNNSS）、鼻结膜炎生活质量量表（RQLQ）、鼻炎控制评估测试（RCAT）评分；于治疗前、治疗后，检测嗜酸性粒细胞（EOS）计数、免疫球蛋白E（IgE）、白细胞介素（IL）-4、IL-6、IL-17水平，并于治疗后评价临床疗效，于随访时评定复发率。

结果：

患者治疗后、随访时TNSS、TNNSS、RQLQ评分均较治疗前降低（

0.05），RCAT评分较治疗前升高（

0.05）；患者随访时与治疗后TNSS、TNNSS、RQLQ、RCAT评分比较，差异无统计学意义（

0.05）。治疗后，患者全血EOS计数及血清IgE、IL-4、IL-6、IL-17水平均较治疗前降低（

0.05）。治疗后，31例患者中显效17例，有效12例，无效2例，总有效率为93.5%；随访时，复发2例，复发率为6.9%。

结论：

麦粒灸联合透刺医用臭氧注射可改善AR症状，降低复发率及提升患者生活质量，其机制可能与调节免疫相关指标有关。

Abstract

Objective

To observe the clinical efficacy of combination therapy of wheat-grained sized cone moxibustion and point-to-point needle insertion with medical ozone penetrating injection for allergic rhinitis (AR) and its effect on inflammation-related indexes.

Methods

Thirty-one patients with persistent AR were enrolled. The patients received medical ozone injection at bilateral Yingxiang (LI20)-to-Shangyingxiang (EX-HN8)

and wheat-grained sized cone moxibustion at Dazhui (GV14)

twice a week (with a 3-day interval) for 4 consecutive weeks. The total nasal symptoms score (TNSS)

total non-nasal symptom score (TNNSS)

rhinoconjunctivitis quality of life questionnaire (RQLQ)

and rhinitis control assessment test (RCAT) scores were evaluated before treatment

after treatment

and at the 8-week follow-up. Levels of eosinophil (EOS) count

immunoglobulin E (IgE)

interleukin (IL)-4

IL-6

and IL-17 were measured before and after treatment. Clinical efficacy was evaluated after treatment

and the recurrence rate was assessed at follow-up.

Results

Compared with those before treatment

the TNSS

TNNSS

and RQLQ scores were decreased (

0.05)

while the RCAT score was increased (

0.05) after treatment and at follow-up. There were no statistically significant differences in above indexes between the post-treatment and follow-up (

0.05). After treatment

the whole blood EOS count and serum levels of IgE

IL-4

IL-6

and IL-17 were decreased compared with those before treatment (

0.05). After treatment

17 cases were markedly effective

12 cases were effective

and 2 cases were ineffective

resulting in a total effective rate of 93.5%. At follow-up

2 cases relapsed

and the recurrence rate was 6.9%.

Conclusion

Combination therapy of wheat-grained sized cone moxibustion and point-to-point needle insertion with medical ozone injection can improve AR symptoms

reduce the recurrence rate

and enhance the quality of life. The mechanism may be associated with the regulation of immune-related indexes.

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