Acupuncture at <italic style="font-style: italic">yinsanzhen</italic> combined with auricular point sticking in the treatment of primary dysmenorrhea: a randomized controlled trial

LU Chunxia; FENG Lin; LUO Hong; CUI Jin; CHEN Bo

doi:10.13703/j.0255-2930.20241205-k0001

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Acupuncture at yinsanzhen combined with auricular point sticking in the treatment of primary dysmenorrhea: a randomized controlled trial

Clinical Research | 更新时间：2025-06-13

- Acupuncture at yinsanzhen combined with auricular point sticking in the treatment of primary dysmenorrhea: a randomized controlled trial
- Chinese Acupuncture & Moxibustion Vol. 45, Issue 6, Pages: 761-765(2025)
- 作者机构：
  
  贵州中医药大学针灸推拿学院，贵阳 550025
  贵州中医药大学第一附属医院针灸科，贵阳 550001
- 作者简介：
- 基金信息：
- DOI：10.13703/j.0255-2930.20241205-k0001
  CLC：
- Received：05 December 2024，
  
  Online First：28 March 2025，
  
  Published：12 June 2025
- 稿件说明：
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LU Chunxia, FENG Lin, LUO Hong, et al. Acupuncture at yinsanzhen combined with auricular point sticking in the treatment of primary dysmenorrhea: a randomized controlled trial[J]. Chinese Acupuncture & Moxibustion, 2025, 45(6): 761-765. DOI: 10.13703/j.0255-2930.20241205-k0001.
DOI：

LU Chunxia, FENG Lin, LUO Hong, et al. Acupuncture at yinsanzhen combined with auricular point sticking in the treatment of primary dysmenorrhea: a randomized controlled trial[J]. Chinese Acupuncture & Moxibustion, 2025, 45(6): 761-765. DOI: 10.13703/j.0255-2930.20241205-k0001. DOI：

摘要

目的：

观察“阴三针”结合耳穴贴压治疗原发性痛经（PDM）的临床疗效。

方法：

将60例PDM患者随机分为观察组和对照组，各30例。观察组采用“阴三针”针刺结合耳穴贴压治疗，针刺取“阴三针”（关元及双侧归来、三阴交），每天1次，连续5 d；耳穴贴压取肝、肾、内分泌等，隔日1次，双耳交替进行，治疗3次，均在月经来潮前5 d开始治疗。对照组在月经第1天予布洛芬缓释胶囊治疗，连续3 d。两组均治疗3个月经周期。比较两组患者治疗前后及治疗结束后2个月月经来潮（随访）时Cox痛经症状量表（CMSS）、视觉模拟量表（VAS）评分，于治疗前后检测两组患者血清前列腺素（PG）F2α、PGE2含量，评价两组临床疗效和安全性。

结果：

治疗后及随访时，两组患者CMSS严重程度和持续时间评分、VAS评分均较治疗前降低（

0.05），且观察组低于对照组（

0.05）。治疗后，两组患者血清PGF2α含量降低、PGE2含量升高（

0.05）。观察组总有效率为93.3%（28/30），高于对照组的80.0%（24/30，

0.05）。两组均未出现不良反应。

结论：

“阴三针”结合耳穴贴压可以有效改善PDM的疼痛症状，缓解疼痛程度，缩短疼痛时间，可能是通过降低血清PGF2α含量、升高PGE2含量来发挥治疗作用。

Abstract

Objective

To observe the clinical effect of acupuncture at

yinsanzhen

combined with auricular point sticking on primary dysmenorrhea (PDM).

Methods

Sixty patients with PDM were randomly divided into an observation group and a control group

with 30 cases in each group. Patients in the observation group were treated with acupuncture at

yinsanzhen

combined with auricular point sticking. The acupuncture was given at

yinsanzhen

(Guanyuan [CV4

]

and bilateral Guilai [ST29

]

Sanyinjiao [SP6

]

) once daily for 5 consecutive days. Auricular point sticking was applied to gan (CO

)

shen (CO

)

neifenmi (CO

)

etc. every other day

alternated between ears

totaling 3 sessions. All treatments were started 5 days before menstruation. Patients in the control group were treated with ibuprofen sustained-release capsules on the first day of menstruation for 3 consecutive days. Both groups were treated for 3 menstrual cycles. The scores of Cox menstrual symptom scale (CMSS) and visual analogue scale (VAS) were compared between the two groups before and after treatment and at the second menstrual cycle after treatment completion (follow-up). The serum contents of prostaglandin (PG) F2α and PGE2 were detected before and after treatment

and the clinical effect and safety of the two groups were evaluated.

Results

After treatment and during follow-up

the CMSS severity and duration scores and VAS scores of the two groups were lower than those before treatment (

0.05 )

and the scores in the observation group were lower than those in the control group (

0.05). After treatment

the serum contents of PGF2α were decreased

and the contents of PGE2 were increased (

0.05) in the two groups. The total effective rate of the observation group was 93.3% (28/30)

which was higher than 80.0% (24/30) of the control group (

0.05). There were no adverse reactions in both groups.

Conclusion

Yinsanzhen

combined with auricular point sticking

can effectively improve the pain symptoms

relieve the degree of pain and shorten the duration of pain in patients with PDM

which may play a therapeutic role by reducing the content of serum PGF2α and increasing the content of serum PGE2.

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Acupuncture at yinsanzhen combined with auricular point sticking in the treatment of primary dysmenorrhea: a randomized controlled trial

DOI：10.13703/j.0255-2930.20241205-k0001

摘要

Abstract

关键词

Keywords

references