Acupoint thread-embedding therapy of regulating governor vessel, dispersing lung, and suppressing reflux for gastroesophageal reflux cough: a randomized controlled trial

TANG Mingjie; LU Wen; ZHANG Xiaoni; GAO Jiawei; WEI Xinchang; LU Jin; ZHU Jia; FENG Yulu; JIAO Lejing; XIA Xiaofang; ZHOU Zhi; CHEN Zhaoming

doi:10.13703/j.0255-2930.20241225-k0001

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Acupoint thread-embedding therapy of regulating governor vessel, dispersing lung, and suppressing reflux for gastroesophageal reflux cough: a randomized controlled trial

Clinical Research | 更新时间：2025-08-14

- Acupoint thread-embedding therapy of regulating governor vessel, dispersing lung, and suppressing reflux for gastroesophageal reflux cough: a randomized controlled trial
- Chinese Acupuncture & Moxibustion Vol. 45, Issue 8, Pages: 1047-1052(2025)
- 作者机构：
  
  南京中医药大学，江苏南京　210023
  连云港市第一人民医院
  南京中医药大学附属南京市中医院针灸科，江苏南京　210022
  江苏省中医院
  南京市高淳中医院
  南京市鼓楼区江东社区卫生服务中心
- 作者简介：
- 基金信息：
- DOI：10.13703/j.0255-2930.20241225-k0001
  CLC：
- Received：25 December 2024，
  
  Online First：30 May 2025，
  
  Published：12 August 2025
- 稿件说明：
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TANG Mingjie, LU Wen, ZHANG Xiaoni, et al. Acupoint thread-embedding therapy of regulating governor vessel, dispersing lung, and suppressing reflux for gastroesophageal reflux cough: a randomized controlled trial[J]. Chinese Acupuncture & Moxibustion, 2025, 45(8): 1047-1052.
DOI：

TANG Mingjie, LU Wen, ZHANG Xiaoni, et al. Acupoint thread-embedding therapy of regulating governor vessel, dispersing lung, and suppressing reflux for gastroesophageal reflux cough: a randomized controlled trial[J]. Chinese Acupuncture & Moxibustion, 2025, 45(8): 1047-1052. DOI： 10.13703/j.0255-2930.20241225-k0001.

摘要

目的：

观察通督宣肺降逆法穴位埋线治疗胃食管反流性咳嗽（GERC）的临床疗效。

方法：

将120例GERC患者随机分为观察组（60例，脱落1例）和对照组（60例，剔除1例）。观察组采用通督宣肺降逆法穴位埋线治疗，穴取督脉阳性反应点，若未探测到阳性反应点，则取大椎、风户、神道、灵台、至阳，每2周1次。对照组予雷贝拉唑肠溶胶囊口服，每次20 mg，每天早晚各1次。两组均治疗6周。观察两组患者治疗前后咳嗽症状评分、反流性疾病问卷（RDQ）评分、莱赛斯特咳嗽生命质量问卷（LCQ）评分，并比较两组患者临床疗效。

结果：

治疗后，两组患者咳嗽症状评分、RDQ各单项症状评分及总分均较治疗前降低（

0.001），LCQ评分较治疗前升高（

0.001）；观察组患者咳嗽症状评分、RDQ胸痛、反食评分及总分低于对照组（

0.05），LCQ评分高于对照组（

0.05）。观察组总有效率为94.9%（56/59），高于对照组的84.7%（50/59，

0.05）。

结论：

通督宣肺降逆法穴位埋线可有效改善GERC患者的咳嗽症状和反流症状，提高生存质量。

Abstract

Objective

To observe the clinical efficacy of acupoint thread-embedding therapy of regulating governor vessel

dispersing lung

and suppressing reflux for gastroesophageal reflux cough (GERC).

Methods

A total of 120 GERC patients were randomly assigned to an observation group (60 cases

1 case dropped out) and a control group (60 cases

1 case was eliminated). The observation group received acupoint thread-embedding treatment at positive response points of governor vessel. If no such points were detected

the following acupoints were used: Dazhui (GV14)

Fenghu (Extra)

Shendao (GV11)

Lingtai (GV10)

and Zhiyang (GV9). Treatment was administered once every two weeks. The control group received oral rabeprazole enteric capsules at 20 mg twice daily. All the treatment was given for 6 weeks. Clinical outcomes were assessed using cough symptom score

reflux disease questionnaire (RDQ) score

and Leicester cough questionnaire (LCQ) score before and after treatment in the two groups. Clinical efficacy was also compared between the two groups.

Results

After treatment

both groups showed decreased cough symptom scores and the each item scores and total scores of RDQ (

0.001)

and increased LCQ scores (

0.001) compare with those before treatment. The observation group exhibited lower cough symptom score and chest pain

reflux and total score of RDQ

and higher LCQ score compared to those in the control group (

0.05). The total effective rate in the observation group was 94.9% (56/59)

which was higher than 84.7% (50/59) in the control group (

0.05).

Conclusion

Acupoint thread-embedding therapy of regulating governor vessel

dispersing lung

and suppressing reflux could effectively alleviate cough and reflux symptoms in patients with GERC and improve their quality of life.

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