Lying needling from <italic style="font-style: italic">Nanjing</italic> for malar melasma: a randomized controlled trial

ZHAO Xiaofan; GU Youjia; MAN Jiaqi; DUAN Bingyu; YANG Mengyi; YU Jiayue; HOU Wenguang

doi:10.13703/j.0255-2930.20250217-k0003

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Lying needling from Nanjing for malar melasma: a randomized controlled trial

Clinical Research | 更新时间：2026-07-09

- Lying needling from Nanjing for malar melasma: a randomized controlled trial
- Chinese Acupuncture & Moxibustion Vol. 46, Issue 7, Pages: 1061-1067(2026)
- 作者机构：
  
  上海中医药大学附属岳阳中西医结合医院针灸科，上海　200437
- 作者简介：
- 基金信息：
- DOI：10.13703/j.0255-2930.20250217-k0003
  CLC：
- Received：17 February 2025，
  
  Online First：18 May 2026，
  
  Published：12 July 2026
- 稿件说明：
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ZHAO Xiaofan, GU Youjia, MAN Jiaqi, et al. Lying needling from Nanjing for malar melasma: a randomized controlled trial[J]. Chinese Acupuncture & Moxibustion, 2026, 46(7): 1061-1067. DOI: 10.13703/j.0255-2930.20250217-k0003.
DOI：

ZHAO Xiaofan, GU Youjia, MAN Jiaqi, et al. Lying needling from Nanjing for malar melasma: a randomized controlled trial[J]. Chinese Acupuncture & Moxibustion, 2026, 46(7): 1061-1067. DOI: 10.13703/j.0255-2930.20250217-k0003. DOI：

摘要

目的：

观察《难经》“卧针刺法”治疗颊型黄褐斑的临床疗效和安全性。

方法：

将78例颊型黄褐斑患者随机分为卧针刺组（39例，脱落1例）和假针刺组（39例，剔除1例）。两组均予常规护理，卧针刺组予《难经》“卧针刺法”，穴取颊部黄褐斑区和双侧二间、内庭、前谷等；假针刺组予钝头针假针刺，取穴同卧针刺组。两组均每日1次，每周3次，共干预3周。分别于治疗前后观察两组患者黄褐斑面积及严重程度指数（MASI）、皮肤病生活质量指数（DLQI）、皮损症状评分和黄褐斑区体表红外温度，于治疗后评定两组临床疗效及安全性。

结果：

治疗后，卧针刺组患者MASI和皮损症状评分较治疗前降低（

0.001），黄褐斑区体表红外温度较治疗前升高（

0.001）；两组患者DLQI评分较治疗前降低（

0.01，

0.05）。卧针刺组患者治疗前后MASI、皮损症状评分和黄褐斑区体表红外温度差值大于假针刺组（

0.001）。卧针刺组有效率为89.5%（34/38），高于假针刺组的31.6%（12/38，

0.05）。两组均未出现不良事件。

结论：

《难经》“卧针刺法”可有效治疗颊型黄褐斑，改善患者临床症状和生活质量，安全性好。

Abstract

Objective

To observe the clinical efficacy and safety of lying needling from

Nanjing

(

Classic of Difficult Issues

) in treating malar melasma.

Methods

A total of 78 patients with malar melasma were randomized into a lying needling group (39 cases

1 case dropped out) and a sham acupuncture group (39 cases

1 case was eliminated). Routine care was adopted in both groups. In the lying needling group

lying needling from

Nanjing

was applied

the malar melasma area and bilateral Erjian (LI2)

Neiting (ST44)

Qiangu (SI2)

etc. were selected. In the sham acupuncture group

sham acupuncture with blunt-tip needle was applied at the same acupoints. Both groups were treated once daily

3 times a week for 3 weeks. The scores of melasma area and severity index (MASI)

dermatology life quality index (DLQI)

skin lesion symptom

and infrared temperature of the melasma area were observed before and after treatment; the clinical efficacy and safety were evaluated after treatment in both groups.

Results

After treatment

the MASI and skin lesion symptom scores were decreased compared with those before treatment (

0.001)

and the infrared temperature of the melasma area was increased compared with that before treatment in the lying needling group (

0.001); the DLQI scores were decreased compared with those before treatment in both groups (

0.01

0.05). The differences in the MASI score

skin lesion symptom score

and infrared temperature of the melasma area before and after treatment in the lying needling group were greater than those in the sham acupuncture group (

0.001). The total effective rate was 89.5% (34/38) in the lying needling group

which was higher than 31.6% (12/38) in the sham acupuncture group (

0.05). No adverse events occurred in the two groups.

Conclusion

Lying needling from

Nanjing

can effectively treat malar melasma

improve patients' clinical symptoms and quality of life

with good safety.

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⁰

Lying needling from Nanjing for malar melasma: a randomized controlled trial

DOI：10.13703/j.0255-2930.20250217-k0003

摘要

Abstract

关键词

Keywords

references