Clinical dose-effect study of acupuncture at Lianquan (CV23) with different frequencies of twirling manipulation for post-ischemic stroke aphasia

CHEN Junjie; JIANG Hailun; DENG Shizhe; MENG Zhihong

doi:10.13703/j.0255-2930.20250319-k0003

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Clinical dose-effect study of acupuncture at Lianquan (CV23) with different frequencies of twirling manipulation for post-ischemic stroke aphasia

Clinical Research | 更新时间：2026-04-16

- Clinical dose-effect study of acupuncture at Lianquan (CV23) with different frequencies of twirling manipulation for post-ischemic stroke aphasia
- Chinese Acupuncture & Moxibustion Vol. 46, Issue 4, Pages: 483-490(2026)
- 作者机构：
  
  天津中医药大学第一附属医院，天津　300381
  中医国家临床医学研究中心，天津　300381
  天津中医药大学研究生院，天津　301617
- 作者简介：
- 基金信息：
- DOI：10.13703/j.0255-2930.20250319-k0003
  CLC：
- Received：19 March 2025，
  
  Online First：30 January 2026，
  
  Published：12 April 2026
- 稿件说明：
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CHEN Junjie, JIANG Hailun, DENG Shizhe, et al. Clinical dose-effect study of acupuncture at Lianquan (CV23) with different frequencies of twirling manipulation for post-ischemic stroke aphasia[J]. Chinese Acupuncture & Moxibustion, 2026, 46(4): 483-490.
DOI：

CHEN Junjie, JIANG Hailun, DENG Shizhe, et al. Clinical dose-effect study of acupuncture at Lianquan (CV23) with different frequencies of twirling manipulation for post-ischemic stroke aphasia[J]. Chinese Acupuncture & Moxibustion, 2026, 46(4): 483-490. DOI： 10.13703/j.0255-2930.20250319-k0003.

摘要

目的：

观察不同频率捻转手法针刺廉泉对缺血性卒中后失语（PSA）的影响。

方法：

将105例缺血性PSA患者随机分为低频捻转组（LT组，35例，脱落1例）、高频捻转组（HT组，35例，脱落3例）和假针刺组（SA组，35例，脱落2例）。3组患者均接受脑卒中常规治疗，在此基础上，LT组施以“醒脑开窍”针刺法并在廉泉行低频率捻转刺激（60次/min），HT组施以“醒脑开窍”针刺法并在廉泉行高频率捻转刺激（120次/min），SA组施以非经非穴浅刺。每日1次，每周5次，共治疗6周。分别于治疗前后采用西方失语症成套测验（WAB）、波士顿诊断性失语症检查（BDAE）、美国国立卫生研究院卒中量表（NIHSS）和脑卒中失语症生活质量量表（SAQOL-39）对各组患者语言功能、神经功能和生活质量进行评估，并评定各组临床疗效。

结果：

治疗后，除SA组SAQOL-39沟通、社会心理评分外，各组患者WAB评分、BDAE分级、SAQOL-39评分均较治疗前提高（

0.05），NIHSS评分较治疗前降低（

0.05）。治疗后，除SAQOL-39生理评分外，LT组WAB评分、BDAE分级、SAQOL-39评分均高于SA组（

0.05），NIHSS评分低于SA组（

0.05）；HT组西方失语症成套测验失语商（WAB-AQ）评分、WAB听语理解评分、BDAE分级和SAQOL-39沟通评分高于SA组（

0.05）；LT组WAB-AQ评分、WAB自发言语评分和SAQOL-39沟通评分高于HT组（

0.05），NIHSS评分低于HT组（

0.05）。LT组总有效率为82.35%（28/34），HT组总有效率为71.88%（23/32），均高于SA组的54.55%（18/33，

0.05）。

结论：

与高频率捻转手法针刺廉泉比较，低频率捻转手法改善缺血性PSA患者语言功能、神经缺损和生活质量的效果更好。

Abstract

Objective

To observe the effect of acupuncture at Lianquan (CV23) with different frequencies of twirling manipulation on post-ischemic stroke aphasia.

Methods

A total of 105 patients with post-ischemic stroke aphasia were randomly divided into a low-frequency twirling acupuncture group (LT group

35 cases

1 case dropped out)

a high-frequency twirling acupuncture group (HT group

35 cases

3 cases dropped out) and a sham acupuncture group (SA group

35 cases

2 cases dropped out). All three groups received conventional stroke treatment. On this basis

the LT group was treated with

Xingnao Kaiqiao

acupuncture (regaining consciousness and opening orifices)

and low-frequency twirling stimulation (60 times/min) was performed at Lianquan (CV23); the HT group was treated with

Xingnao Kaiqiao

acupuncture

and high-frequency twirling stimulation (120 times/min) was performed at Lianquan (CV23); and the SA group was treated with shallow needling at non-meridian and non-acupoint points. The frequency of treatment was once a day

5 times per week for a total of 6 weeks. Before and after treatment

the Western aphasia battery (WAB)

Boston diagnostic aphasia examination (BDAE)

National Institutes of Health stroke scale (NIHSS) and stroke and aphasia quality of life scale-39 (SAQOL-39) were used to evaluate the language function

neurological function and quality of life

and the clinical efficacy was evaluated in the three groups.

Results

After treatment

except for the communication and psychosocial scores of SAQOL-39 in the SA group

the WAB scores

BDAE grade

and SAQOL-39 scores were increased compared with those before treatment (

0.05)

and the NIHSS scores were decreased compared with those before treatment (

0.05) in the three groups. After treatment

except for the physiological score of SAQOL-39

the WAB scores

BDAE grade

and SAQOL-39 scores in the LT group were higher than those in the SA group (

0.05)

and the NIHSS score in the LT group was lower than that in the SA group (

0.05); the WAB-aphasia quotient (WAB-AQ) score

auditory comprehension score of WAB

BDAE grade

and communication score of SAQOL-39 in the HT group were higher than those in the SA group (

0.05); the WAB-AQ score

spontaneous speech score of WAB

and communication score of SAQOL-39 in the LT group were higher than those in the HT group (

0.05)

and the NIHSS score in the LT group was lower than that in the HT group (

0.05). The total clinical effective rate of the LT group was 82.35% (28/34)

that of the HT group was 71.88% (23/32)

and that of the SA group was 54.55% (18/33)

the total clinical effective rates of the LT group and the HT group were higher than that of the SA group (

0.05).

Conclusion

Compared with the high-frequency twirling manipulation acupuncture at Lianquan (CV23)

the low-frequency twirling manipulation acupuncture has a better effect in improving the language function

neurological function and quality of life in patients with post-ischemic stroke aphasia.

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