Effect of body mass index on the efficacy of acupuncture for discogenic sciatica: a secondary analysis of a multicenter randomized controlled trial

ZHANG Dantong; SHI Guangxia; YAN Shiyan; LI Shuangjing; WANG Yiran; TU Jianfeng; LIU Cunzhi

doi:10.13703/j.0255-2930.20250402-0001

您当前的位置：

首页 >

文章列表页 >

Effect of body mass index on the efficacy of acupuncture for discogenic sciatica: a secondary analysis of a multicenter randomized controlled trial

Clinical Research | 更新时间：2026-04-16

- Effect of body mass index on the efficacy of acupuncture for discogenic sciatica: a secondary analysis of a multicenter randomized controlled trial
- Chinese Acupuncture & Moxibustion Vol. 46, Issue 4, Pages: 559-564(2026)
- 作者机构：
  
  北京中医药大学针灸推拿学院，北京　100029
  北京中医药大学国际针灸创新研究院，北京　100029
- 作者简介：
- 基金信息：
- DOI：10.13703/j.0255-2930.20250402-0001
  CLC：
- Received：02 April 2025，
  
  Online First：12 September 2025，
  
  Published：12 April 2026
- 稿件说明：
移动端阅览
ZHANG Dantong, SHI Guangxia, YAN Shiyan, et al. Effect of body mass index on the efficacy of acupuncture for discogenic sciatica: a secondary analysis of a multicenter randomized controlled trial[J]. Chinese Acupuncture & Moxibustion, 2026, 46(4): 559-564.
DOI：

ZHANG Dantong, SHI Guangxia, YAN Shiyan, et al. Effect of body mass index on the efficacy of acupuncture for discogenic sciatica: a secondary analysis of a multicenter randomized controlled trial[J]. Chinese Acupuncture & Moxibustion, 2026, 46(4): 559-564. DOI： 10.13703/j.0255-2930.20250402-0001.

摘要

目的：

探讨体质量指数（BMI）对针刺治疗椎间盘源性坐骨神经痛疗效的影响。

方法：

对一项多中心随机对照试验数据进行二次分析。试验将216例椎间盘源性坐骨神经痛患者随机分为针刺组（108例，脱落4例）和假针组（108例，脱落12例），针刺组以双侧大肠俞和关元俞为主穴，根据经络辨证选择5个配穴；假针组选择7个非经非穴点。每次治疗30 min，治

疗4周，共10次。将各组患者根据BMI分为两个亚组，即体型正常型（BMI

24 kg/m

）与超重和肥胖型（BMI≥24 kg/m

）。分别于治疗前后观察两组不同BMI患者腿痛视觉模拟量表（VAS）评分和Oswestry功能障碍指数（ODI）评分，并分析BMI和治疗方法的交互作用。

结果：

体型正常型患者113例，超重和肥胖型患者103例，均为女性人数占比更高。针刺组体型正常型患者及超重和肥胖型患者腿痛VAS评分和ODI评分治疗前后差值均大于假针组（

0.001，

0.05）。治疗后，在腿痛VAS评分和ODI评分方面，BMI和治疗方法不存在交互作用（

0.05）。

结论：

针刺对不同BMI椎间盘源性坐骨神经痛患者均有效，且针刺疗效不受BMI影响。

Abstract

Objective

To explore the effect of body mass index (BMI) on the efficacy of acupuncture for discogenic sciatica.

Methods

A secondary analysis was conducted based on data from a multicenter randomized controlled trial. A total of 216 patients with discogenic sciatica were randomly assigned to an acupuncture group (108 cases

4 cases dropped out) and a sham acupuncture group (108 cases

12 cases dropped out). The patients in the acupuncture group were treated with acupuncture

bilateral Dachangshu (BL25) and Guanyuanshu (BL26) were selected as the main points

with five additional acupoints based on meridian syndrome differentiation. The patients in the sham acupuncture group were treated with acupuncture at seven non-meridian and non-acupoint points. Each treatment lasted 30 min

with a total of 10 sessions for 4 weeks. Patients in each group were further divided into two subgroups according to BMI: normal body type (BMI

24 kg/m

) and overweight/obese type (BMI≥24 kg/m

). Visual analogue scale (VAS) score for leg pain and Oswestry disability index (ODI) score were recorded before and after treatment in the two BMI subgroups. The interaction between BMI and treatment method was also analyzed.

Results

There were 113 patients in the normal BMI subgroup and 103 in the overweight/obese subgroup

with a higher proportion of female patients. In the acupuncture group

e differences between pre-treatment and post-treatment leg pain VAS scores and ODI scores in both normal BMI patients and overweight/obese patients were greater than those in the sham acupuncture group (

0.001

0.05). After treatment

no interaction was found between BMI and treatment method in terms of VAS and ODI scores (

0.05).

Conclusion

Acupuncture is effective in treating discogenic sciatica patients regardless of BMI

and its efficacy is not influenced by BMI.

关键词

Keywords

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Interaction between depression and insomnia under acupuncture treatment: a secondary analysis of a randomized controlled trial

Research progress on the regulatory mechanisms of inflammatory signaling pathways in acupuncture treatment for ischemic stroke

Research status and prospects of electroencephalogram characteristics in acupuncture for cognitive dysfunction

Professor YIN Kejing′s clinical experience in treating Meige′s syndrome with four-penetrating Yangbai (GB14) combined with double-needle connection technique

Experimental studies on acupuncture-moxibustion for irritable bowel syndrome in the past five years: a literature analysis

Related Author

WANG Shanze

GAO Jinfeng

WU Bingxin

WU Qian

WEN Xiuyun

NING Baile

LIANG Xuesong

FU Wenbin

Related Institution

Second Clinical Medical College, Guangzhou University of CM

Clinical College of Acupuncture-Moxibustion and Rehabilitation, Guangzhou University of CM

College of Health, Guangdong Pharmaceutical University

Second Clinical Medical College, Guangzhou University of TCM

Clinical College of Acupuncture-Moxibustion and Rehabilitation, Guangzhou University of TCM

⁰