Effect of acupuncture based on the theory of "exterior-interior relationship between lung and large intestine" on acute exacerbation of bronchial asthma

LIU Xuan; ZHANG Zhiguo; QIAO Shubin; TONG Yaozhi; WANG Chuan; ZHANG Hongchun

doi:10.13703/j.0255-2930.20250429-k0002

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Effect of acupuncture based on the theory of "exterior-interior relationship between lung and large intestine" on acute exacerbation of bronchial asthma

Clinical Research | 更新时间：2026-04-16

- Effect of acupuncture based on the theory of "exterior-interior relationship between lung and large intestine" on acute exacerbation of bronchial asthma
- Chinese Acupuncture & Moxibustion Vol. 46, Issue 4, Pages: 523-529(2026)
- 作者机构：
  
  北京市丰台中西医结合医院呼吸与危重症医学科，北京　100072
  中国中医科学院中医基础理论研究所
  中日友好医院中医肺病一部，北京　100029
- 作者简介：
- 基金信息：
- DOI：10.13703/j.0255-2930.20250429-k0002
  CLC：
- Received：29 April 2025，
  
  Online First：12 November 2025，
  
  Published：12 April 2026
- 稿件说明：
移动端阅览
LIU Xuan, ZHANG Zhiguo, QIAO Shubin, et al. Effect of acupuncture based on the theory of "exterior-interior relationship between lung and large intestine" on acute exacerbation of bronchial asthma[J]. Chinese Acupuncture & Moxibustion, 2026, 46(4): 523-529.
DOI：

LIU Xuan, ZHANG Zhiguo, QIAO Shubin, et al. Effect of acupuncture based on the theory of "exterior-interior relationship between lung and large intestine" on acute exacerbation of bronchial asthma[J]. Chinese Acupuncture & Moxibustion, 2026, 46(4): 523-529. DOI： 10.13703/j.0255-2930.20250429-k0002.

摘要

目的：

在常规西医治疗基础上，观察基于“肺与大肠相表里”理论针刺对支气管哮喘急性发作期的影响。

方法：

将48例支气管哮喘急性发作期患者随机分为观察组（24例，2例剔除）和对照组（24例，1例剔除）。对照组采用常规西医治疗，观察组在对照组治疗基础上联合基于“肺与大肠相表里”理论的针刺治疗，穴取双侧肺俞、大肠俞、定喘，每次20 min，隔日1次，每周3次，共治疗14 d。分别于治疗前后评估两组患者呼气峰流速（PEF）、第1秒用力呼气容积（FEV1）、第1秒用力呼气容积占用力肺活量比值（FEV1/FVC）、哮喘控制问卷（ACQ5）评分及中医症状评分。

结果：

治疗后，两组患者PEF、FEV1、FEV1/FVC均较治疗前升高（

0.01，

0.05），ACQ5评分及中医症状评分均较治疗前降低（

0.01）；观察组患者PEF、ACQ5评分及中医症状评分治疗前后差值大于对照组（

0.05，

0.01）。

结论：

在常规西医治疗基础上，基于“肺与大肠相表里”理论针刺可改善支气管哮喘急性发作期患者肺功能，缓解临床症状。

Abstract

Objective

To observe the effect of acupuncture based on the theory of "exterior-interior relationship between lung and large intestine" on acute exacerbation of bronchial asthma on the basis of the conventional western medicine therapy.

Methods

Forty-eight patients with acute exacerbation of bronchial asthma were randomly divided into an observation group (24 cases

2 cases were eliminated) and a control group (24 cases

1 case was eliminated). The control group was treated with conventional western medicine therapy. Based on the treatment of the control group

the patients in the observation group were treated with acupuncture based on the theory of "exterior-interior relationship between lung and large intestine"

bilateral Feishu (BL13)

Dachangshu (BL25) and Dingchuan (EX-B1) were selected

20 min each session，once every other day

3 times a week for 14 days. Before and after treatment

the peak expiratory flow (PEF)

forced expiratory volume in one second (FEV1)

FEV1/forced vital capacity (FVC)

asthma control questionnaire 5 (ACQ5) score and TCM symptom score were observed in the two groups.

Results

After treatment

the PEF

FEV1 and FEV1/FVC in the two groups were increased compared with those before treatment (

0.01

0.05)，the ACQ5 scores and TCM symptom scores were decreased compared with those before treatment (

0.01); the changes of PEF

ACQ5 score and TCM symptom score in the observation group were larger than those in the control group (

0.05

0.01).

Conclusion

On the basis of the conventional western medicine therapy

acupuncture based on the theory of "exterior-interior relationship between lung and large intestine" could improve pulmonary function and alleviate clinical symptoms in patients with acute exacerbation of bronchial asthma.

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