acupuncture in treatment of postherpetic neuralgia (PHN).
Methods
2
A total of 106 patients with PHN were randomly divided into a Tongyuan electroacupuncture group (53 cases
3 cases dropped out) and a conventional electroacupuncture group (53 cases
4 cases dropped out
2 cases were eliminated). In the Tongyuan electroacupuncture group
Baihui (GV20)
Yintang (GV24
+
)
Shuigou (GV26)
Qihai (CV6)
Guanyuan (CV4)
ashi
points and bilateral Xinshu (BL15)
Geshu (BL17)
Ganshu (BL18)
Pishu (BL20)
Tianshu (ST25) were selected
and 5 to 6 pairs of acupoints were selected to connect the electroacupuncture therapeutic apparatus; in the conventional electroacupuncture group
ashi
points and Jiaji points (EX-B2) of the relevant ganglion segments in the affected area were selected
and Jiaji points (EX-B2) and
ashi
points were connected to the electroacupuncture therapeutic apparatus. In both groups
dense-disperse waves were selected at a frequency of 2 Hz/100 Hz and a current of 2 mA. The needles were retained for 30 min per session
once daily. Five sessions constituted one treatment course
with a 2-day interval between courses. A total of four treatment courses were administered. The simplified McGill pain questionnaire (SF-MPQ) score (including the pain rating index [PRI
]
score
visual analogue scale [VAS
]
score
and present pain intensity [PPI
]
score) of both groups were observed before treatment
after 2 weeks of treatment
and after 4 weeks of treatment. The Pittsburgh sleep quality index (PSQI) score
Hamilton anxiety scale (HAMA) score
and Hamilton depression scale (HAMD) score of both groups were observed before treatment and after 4 weeks of treatment. Clinical efficacy was evaluated after treatment
and pain recurrence was followed up at 3 months after treatment completion.
Results
2
Compared with before treatment
the sub-scores and total scores of the SF-MPQ in both groups decreased after 2 and 4 weeks of treatment (
P
<
0.05)
and the scores after 4 weeks of treatment were lower than those after 2 weeks of treatment (
P
<
0.05). After 2 weeks of treatment
the scores of VAS and PPI
and the total score of SF-MPQ in the Tongyuan electroacupuncture group were lower than those in the conventional electroacupuncture group (
P
<
0.05). After 4 weeks of treatment
all sub-scores and total score of the SF-MPQ in the Tongyuan electroacupuncture group were lower than those in the conventional electroacupuncture group (
P
<
0.05). After treatment
the PSQI
HAMA
and HAMD scores in both groups were lower than those before treatment (
P
<
0.05); the PSQI
HAMA
and HAMD scores in the Tongyuan electroacupuncture group were lower than those in the conventional electroacupuncture group (
P
<
0.05). The total effective rate and marked effective rate in the Tongyuan electroacupuncture group were 90.0% (45/50) and 72.0% (36/50)
respectively
both higher than those in the conventional electroacupuncture group (74.5% [35/47
]
and 44.7% [21/47
]
P
<
0.05). During follow-up
the pain recurrence rate in the Tongyuan electroacupuncture group was 2.2% (1/45)
which was lower than that in the conventional electroacupuncture group (17.1% [6/35
]
P
<
0.05).
Conclusion
2
Tongyuan
acupuncture can alleviate pain
improve sleep disturbances
and ameliorate emotional comorbidities in patients with PHN
and its short-term and long-term efficacy is superior to that of conventional electroacupuncture.