Experimental studies on acupuncture-moxibustion for irritable bowel syndrome in the past five years: a literature analysis

LIN Jie; WENG Zhijun; ZHANG Fang; ZHOU Yi; ZHANG Zijun; LU Yuan; WU Luyi; WU Huangan; CHEN Ziyi; LIU Huirong

doi:10.13703/j.0255-2930.20250826-k0001

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Experimental studies on acupuncture-moxibustion for irritable bowel syndrome in the past five years: a literature analysis

Literature Research | 更新时间：2026-09-15

- Experimental studies on acupuncture-moxibustion for irritable bowel syndrome in the past five years: a literature analysis
- Chinese Acupuncture & Moxibustion Vol. 46, Issue 9, Pages: 1554-1561(2026)
- 作者机构：
  
  上海中医药大学附属岳阳中西医结合医院，上海　200437
  上海市针灸经络研究所，上海　200030
- 作者简介：
- 基金信息：
- DOI：10.13703/j.0255-2930.20250826-k0001
  CLC：
- Received：26 August 2025，
  
  Online First：08 June 2026，
  
  Published：12 September 2026
- 稿件说明：
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LIN Jie, WENG Zhijun, ZHANG Fang, et al. Experimental studies on acupuncture-moxibustion for irritable bowel syndrome in the past five years: a literature analysis[J]. Chinese Acupuncture & Moxibustion, 2026, 46(9): 1554-1561.
DOI：

LIN Jie, WENG Zhijun, ZHANG Fang, et al. Experimental studies on acupuncture-moxibustion for irritable bowel syndrome in the past five years: a literature analysis[J]. Chinese Acupuncture & Moxibustion, 2026, 46(9): 1554-1561. DOI： 10.13703/j.0255-2930.20250826-k0001.

摘要

目的：

梳理针灸治疗肠易激综合征（IBS）的实验研究文献，分析针灸治疗IBS的主要研究方向与进展。

方法：

检索中国期刊全文数据库（CNKI）、万方数据知识服务平台（Wanfang）、维普资讯中文期刊服务平台（VIP）、PubMed及Web of Science数据库中针灸治疗IBS的实验研究文献，筛选时间限定为2020年1月1日至2024年12月31日，并对所有纳入文献进行数据分析。

结果：

共纳入124篇文献，其中腹泻型肠易激综合征（IBS-D）66篇（占比53.23%）；在IBS-D文献中，最常用造模方式为慢急性联合应激（CAS/CACS）和束缚应激联合番泻叶灌胃（各14篇，各占21.21%）；电针应用最多[50.00%（67/134）]；核心穴位为足三里（78次，占比26.17%）、天枢（76次，占比25.50%）、上巨虚（52次，占比17.45%）；内脏敏感性为最常用效应评价指标[81.45%（101/124）]。近5年针灸治疗IBS的研究主要集中在内脏高敏感性调节、炎症因子调控、肠道菌群调节、肠道屏障功能保护、行为和抑郁症状的改善及代谢紊乱调节。

结论：

近5年针灸治疗IBS的机制研究取得一定突破，但在效应评价指标的规范性和造模方法的标准化方面仍有不足，未来研究需优化评价体系、规范造模方法，结合多学科手段深入探究针灸机制。

Abstract

Objective

To sort out the experimental research literature on acupuncture-moxibustion for irritable bowel syndrome (IBS)

and to analyze the main research directions and progress of acupuncture-moxibustion for IBS.

Methods

Experimental research literature on acupuncture-moxibustion for IBS was retrieved from CNKI

Wanfang

VIP

PubMed

and Web of Science databases. The screening period was limited from January 1

2020 to December 31

2024

and data analysis was performed on all included literature.

Results

A total of 124 articles were included

among which 66 articles were on diarrhea-predominant irritable bowel syndrome (IBS-D)

accounting for 53.23%. The most commonly used modeling methods were chronic acute combining stress (CAS/CACS) and restraint stress combined with senna gavage in IBS-D studies

each being reported in 14 articles (each accounting for 21.21%). Electroacupuncture was the most frequently used [50.00%(67/134)]. The core acupoints were Zusanli (ST36) (78 times

26.17%)

Tianshu (ST25) (76 times

25.50%)

and Shangjuxu(ST37) (52 times

17.45%). Visceral sensitivity was the most commonly used effect evaluation index [81.45% (101/124)]. In the past five years

studies on acupuncture-moxibustion for IBS have mainly focused on regulation of visceral hypersensitivity

regulation of inflammatory factors

regulation of intestinal flora

protection of intestinal barrier function

improvement of behavior and depressive symptoms

and regulation of metabolic disorders.

Conclusion

In the past five years

mechanism studies on acupuncture-moxibustion for IBS have achieved certain breakthroughs

but there are still deficiencies in the standardization of effect evaluation indexes and modeling methods. Future studies need to optimize the evaluation system

standardize modeling methods

and combine multidisciplinary approaches to deeply explore the mechanisms of acupuncture and moxibustion.

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