Objective To observe the anti-anxiety effect of electroacupuncture at Baihui（GV 20） and Sishencong（EX-HN 1） in patients with gynecological laparoscopic surgery

and to explore its effect on the anesthetic dosage during anesthesia induction. Methods A total of 270 patients with gynecological laparoscopic surgery were randomized into an electroacupuncture group

a medication group and a control group

90 cases in each group. At 24 h and 2 h before anesthesia induction

electroacupuncture was applied at Baihui（GV 20） and Sishencong（EX-HN 1） in the electroacupuncture group

with continuous wave

100 Hz in frequency. At 30 min before anesthesia induction

midazolam of 0.02 mg/kg was given by intravenous drip in the medication group

while 0.9% sodium chloride solution was given by intravenous drip in the control group. At 10 min before anesthesia induction and 6 h after surgery

the scores of 6 item short form of state-trait anxiety inventory（STAI-S6） and visual analogue scale-anxiety（VAS-A） were observed; at 10 min before anesthesia induction（T1） and observer’s assessment of alertness/sedation scale（OAA/S） grade 4（T2）

mean artery pressure（MAP）

heart rate（HR） and value of bispectral index（BIS） were recorded; the dosage of propofol at T2 was recorded and the surgery related adverse reactions were compared among the 3 groups. Results At 10 min before anesthesia induction and 6h after surgery

the STAI-S6 and VAS-A scores in the electroacupuncture group and the medication group were lower than those in the control group（P<0.05）. Values of BIS at T1 and dosage of propofol at T2 in the electroacupuncture group and the medication group were lower than those in the control group（P<0.05）. There were no statistical differences in MAP

HR and surgery related adverse reactions among the 3 groups（P>0.05）. Conclusion Electroacupuncture at Baihui（GV 20）and Sishencong（EX-HN 1） can effectively relieve the presurgical anxiety in patients with gynecological laparoscopic surgery

and reduce the dosage of propofol

its effect is similar to traditional anti-anxiety drug.