Objective To compare the effect of acupuncture at Huiyin（CV 1） and oral administration of western medication in treatment of chronic severe functional constipation（CSFC）. Methods A total of 64 patients with CSFC were randomly divided into an acupuncture group（32 cases

5 cases dropped off） and a western medication group（32 cases

4 cases dropped off）. Both groups were given routine basic treatment. The acupuncture group was treated by directly puncture of 20-30 mm at Huiyin（CV 1）

once a day for the first 4 weeks

5 times a week

once every other day for the next 4 weeks

3 times a week

totally for 8 weeks. The western medication group was treated with 2 mg prucalopride succinate tablets orally before breakfast every day for 8 weeks. The average number of weekly spontaneous bowel movement（SBM） of the two groups were observed before treatment and 1-8 weeks into treatment. The constipation symptom score before and after treatment

and in follow-up of 1 month after treatment

as well as quality of life [patient assessment of constipation quality of life questionnaire（PAC-QOL） score and the proportion of patients of PAC-QOL score difference before and after treatment≥1] before and after treatment were compared in the two groups. The clinical effects of the two groups were evaluated after treatment and in follow-up. Results Compared before treatment

the average number of weekly SBM in the two groups was increased 1-8 weeks into treatment（P<0.05）. The average number of weekly SBM in the acupuncture group was less than that in the western medication group 1 week into treatment（P<0.05）

and the average number of weekly SBM in the observation group was more than that in the western medication group 4-8 weeks into treatment（P<0.05）. The scores of constipation symptom after treatment and in follow-up and scores of PAC-QOL after-treatment in the two groups were lower than those before treatment（P<0.05）

and those in the acupuncture group were lower than the western medication group（P<0.05）. The proportion of patients of PAC-QOL score difference before and after treatment≥1 in the acupuncture group was higher than that in the west medication group（P<0.05）. The total effective rates after treatment and in follow-up in the acupuncture group were 81.5%（22/27） and 78.3%（18/23）

respectively

which were better than 42.9%（12/28） and 43.5%（10/23） in the western medication group（P<0.05）.Conclusion Acupuncture at Huiyin（CV 1） can effectively increase the number of spontaneous defecation in patients with CSFC

reduce constipation symptoms

improve the quality of life

and the effect after treatment and in follow-up is better than oral western medication.