Objective To evaluate the effect of transcutaneous acupoint electrical stimulation（TEAS） at Neiguan（PC 6）on general anesthesia under preserving spontaneous breathing in thoracoscopic lobectomy. Methods A total of 66 patients of primary lung cancer undergoing thoracoscopic lobectomy were divided to an observation group（33 cases

1 case discontinued） and a control group（33 cases）. In the observation group

TEAS at Neiguan（PC 6） was used 30 min before anesthesia induction till the end of surgery. The surgery time

maximum value of partial pressure of end-tidal carbon dioxide（PETCO

2

） and minimum value of oxygen saturation（SpO

2

） of the two groups were recorded. The dosage of propofol

sufentanil

remifentanil and dexmedetomidine were analyzed. Separately

before induction（T0）

at the start of surgery（T1）

thoracic exploration（T2） and lobectomy（T3）

as well as 30 min（T4） and 60 min（T5） after lobectomy

the mean arterial pressure（MAP）

heart rate（HR）

respiratory rate（RR）

serum cortisol（Cor） and norepinephrine（NE） were measured. The time of post anesthesia care unit（PACU） stay

ambulation

flatus

chest drainage and the incidence of nausea and vomiting were compared between the two groups. Results The maximum value of PETCO

2

the dosage of propofol and remifentanil in the observation group were lower than those in the control group（P

<

0.05

P

<

0.01）

the minimum value of SpO2 in the observation group was higher than that of the control group（P

<

0.01）. At T1-T5

the MAP

HR

serum Cor and NE levels in the observation group were all lower than those in the control group（P

<

0.05）. The ambulation time

the time for the flatus

chest drainage time

and the incidence of nausea and vomiting in the observation group were all lower than those in the control group（P

<

0.001

P

<

0.01）. Conclusion For the general anesthesia under preserving spontaneous breathing in thoracoscopic surgery

TEAS at Neiguan（PC 6） relieves stress response

reduces opioids dosage and promotes postoperative recovery.