The basic biological research of acupuncture originates from clinical practice and serves clinical application. It is the fundamental idea of "acupuncture translational medicine". The animal experiment is indispensable in acupuncture translational medicine

which contributes to simplifying the complex factors affecting the clinical efficacy of acupuncture

observing the effect of the nociceptive stimuli and obtaining the invasive and off-body biomarkers.Focusing on animal experiment

the basic biological research can objectively reveal the structure and function of acupoints

obtain the parameters required by different stimulation methods and clarify the material basis which acupuncture works

so as to provide the references and evidences for acupoint combination and the selection of appropriate stimulation in clinical practice

as well as the development of medical instruments and new drugs.