Objective

2

To compare the clinical efficacy of acupuncture

Chinese medication and combination of acupuncture and medication in the treatment of dry eye complicated with computer vision syndrome (CVS).

Methods

2

A total of 152 patients with dry eye complicated with CVS were randomly divided into an acupuncture-medication group (38 cases

1 case was removed)

an acupuncture group (38 cases

1 case dropped off)

a Chinese medication group (38 cases

1 case was removed)

and a western medication group (38 cases

1 case dropped off). In the western medication group

sodium hyaluronate eye drop combined with esculin and digitalis glycosides eye drop were used. In the acupuncture group

acupuncture was applied at bilateral Taiyang (EX-HN 5)， Cuanzhu (BL 2)

Fengchi (GB 20)

Qime

n (LR 14)

and Hegu (LI 4) etc.

once a day. In the Chinese medication group

Yiqi Congming

decoction formula ganule was given orally

one dose a day. In the acupuncture-medication group

acupuncture combined with

Yiqi Congming

decoction formula granule were used. All groups were treated for 14 d. The non-invasive first tear film break-up time (NIBUT f)

non-invasive average tear film break-up time (NIBUT av)

tear meniscus height (TMH)

ocular surface disease index (OSDI) score

and CVS symptom score were compared between the patients of each group before and after treatment.

Results

2

After treatment

the NIBUT f

NIBUT av

and TMH were increased compared with those before treatment in the patients of the 4 groups (

P

<

0.01); the NIBUT f and NIBUT av in the acupuncture-medication group and the acupuncture group were higher than those in the Chinese medication group and the western medication group (

P

<

0.05)

and the TMH in the acupuncture-medication group and the Chinese medication group were higher than those in the acupuncture group and the western medication group (

P

<

0.05). After treatment

the OSDI scores

the various scores and total scores of CVS (except for head symptom score in the western medication group) were decreased compared with those before treatment in the patients of the 4 groups (

P

<

0.01). The OSDI score

total score

eye symptom score

and body symptom score of CVS in the acupuncture-medication group were lower than those in the acupuncture group

the Chinese medication group

and the western medication group (

P

<

0.01

P

<

0.05)

the head symptom score of the acupuncture-medication group was lower than that in the western medication group (

P

<

0.05)

and the CVS physical symptom scores and mental cognitive symptom scores of the acupuncture-medication group and the acupuncture group were lower than t

hose in the Chinese medication group and the western medication group (

P

<

0.05).

Conclusion

2

Acupuncture has advantages in improving NIBUT f

NIBUT av

and CVS physical symptoms and cognitive symptoms

and the Chinese medication has advantage in improving TMH. The combination of acupuncture and Chinese medication has better effects compared with monotherapy.