
浏览全部资源
扫码关注微信
中国中医科学院针灸研究所,北京100700
胡翔昱,中国中医科学院硕士研究生。E-mail:zyxiangyu@163.com
岗卫娟,研究员。E-mail:gangweijuan@126.com
收稿:2022-11-24,
网络首发:2023-09-19,
纸质出版:2023-11-12
移动端阅览
胡翔昱,修文萃,施兰君等.针灸辅助体外受精胚胎移植的系统评价再评价[J].中国针灸,2023,43(11):1315-1323.
HU Xiang-yu,XIU Wen-cui,SHI Lan-jun,et al.Acupuncture for in vitro fertilization-embryo transfer: an overview of systematic reviews[J].Chinese Acupuncture & Moxibustion,2023,43(11):1315-1323.
胡翔昱,修文萃,施兰君等.针灸辅助体外受精胚胎移植的系统评价再评价[J].中国针灸,2023,43(11):1315-1323. DOI: 10.13703/j.0255-2930.20221124-k0006.
HU Xiang-yu,XIU Wen-cui,SHI Lan-jun,et al.Acupuncture for in vitro fertilization-embryo transfer: an overview of systematic reviews[J].Chinese Acupuncture & Moxibustion,2023,43(11):1315-1323. DOI: 10.13703/j.0255-2930.20221124-k0006.
目的
2
对针灸辅助体外受精胚胎移植(IVF-ET)的系统评价(SR)/Meta分析(MA)进行报告质量、方法学质量和证据质量的再评价。
方法
2
计算机检索中国期刊全文数据库(CNKI)、万方数据知识服务平台(Wanfang)、维普中文期刊服务平台(VIP)、中国生物医学文献数据库(SinoMed)、PubMed、EMbase、Cochrane Library中针灸辅助IVF-ET的SR/MA。检索时限均为建库至2022年9月27日。由2名研究员独立筛选文献、提取资料后,采用PRISMA声明、AMSTAR 2量表和GRADE系统分别评价纳入SR/MA的报告质量、方法学质量和证据质量。
结果
2
共纳入28篇SR/MA,PRISMA评分在8.5~27分。报告质量问题主要表现在方案和注册、检索、研究偏倚、其他分析、局限性、资金支持等方面。纳入研究的方法学质量整体偏低,问题主要集中在条目2、3、7、10、12、16。共85个结局指标纳入GRADE系统进行证据等级评价,大部分证据质量为低或极低,降级的原因主要与研究的局限性、不一致性、不精确性和发表偏倚有关。
结论
2
针灸辅助IVF-ET治疗可以改善不孕患者的妊娠结局,但相关SR/MA的方法学质量和证据质量均较低,建议今后开展更多高质量的研究以提供更可靠的循证依据。
Objective
2
To evaluate the report quality
methodological quality and evidence quality of the systematic reviews and meta-analyses (SRs/MAs) of acupuncture for in vitro fertilization-embryo transfer (IVF-ET).
Methods
2
The SRs/MAs of acupuncture for IVF-ET were searched electronically from databases of CNKI
Wanfang
VIP, SinoMed
PubMed
Embase
Cochrane Library
from inception of each database to September 27th
2022. Two reviewers independently screened the literature and extracted the data. Using PRISMA statement
the AMSTAR 2 scale and the GRADE system
the report quality
methodological quality and evidence quality of the included SRs/MAs were assessed.
Results
2
A total of 28 SRs/MAs were included
with PRISMA scores ranging from 8.5 points to 27 points. The problems of report quality focused on protocol and registration
retrieval
risk of bias in studies
additional analysis
limitations and funding. The methodological quality of included studies was generally low
reflecting on items 2
3
7
10
12 and 16. A total of 85 outcome indexes were included in the GRADE system for evidence grade evaluation. Most of the evidences were low or very low in quality. The reasons for the downgrade were related to study limitations
inconsistency
imprecision and publication bias.
Conclusion
2
Acupuncture therapy improves the outcomes of IVF-ET
but the methodological quality and evidence quality of related SRs/MAs are low. It is recommended to conduct more high-quality studies in the future to provide more reliable evidences.
Vayena E , Rowe P , Griffin D . Current Practices and Controversies in Assisted Reproduction [M ] . Geneva : World Health Organization , 2002 .
Izzo CR , Monteleone PA , Serafini PC . Human reproduction:current status [J ] . Rev Assoc Med Bras , 2015 , 61 ( 6 ): 557 - 559 .
Qiao J , Wang YY , Li XH , et al . A Lancet commission on 70 years of women's reproductive, maternal, newborn, child, and adolescent health in China [J ] . Lancet , 2021 , 397 ( 10293 ): 2497 - 2536 .
Kissin DM , Kawwass JF , Monsour M , et al . Assisted hatching: trends and pregnancy outcomes, United States, 2000-2010 [J ] . Fertil Steril , 2014 , 102 ( 3 ): 795 - 801 .
European IVF-Monitoring Consortium (EIM) for the European Society of Human Reproduction and Embryology (ESHRE) , Wyns C , De Geyter C , et al . ART in Europe, 2017: results generated from European registries by ESHRE [J ] . Hum Reprod Open , 2021 , 2021 ( 3 ): hoab026 .
谢奇君 , 李欣 , 赵纯 , 等 . 辅助生殖技术相关并发症的研究进展 [J ] . 国际生殖健康/计划生育杂志 , 2021 , 40 ( 3 ): 204 - 208 .
Domar AD , Conboy L , Denardo-Roney J , et al . Lifestyle behaviors in women undergoing in vitro fertilization: a prospective study [J ] . Fertil Steril , 2012 , 97 ( 3 ): 697 - 701.e1 .
Cheong Y , Nardo LG , Rutherford T , et al . Acupuncture and herbal medicine in in vitro fertilisation: a review of the evidence for clinical practice [J ] . Hum Fertil , 2010 , 13 ( 1 ): 3 - 12 .
Quan KW , Yu CY , Wen XH , et al . Acupuncture as treatment for female infertility: a systematic review and meta-analysis of randomized controlled trials [J ] . Evid Based Complement Alternat Med , 2022 , 2022 : 3595033 .
Yang H , Hu WH , Xu GX , et al . Transcutaneous electrical acupoint stimulation for pregnancy outcomes in women undergoing in vitro fertilization-embryo transfer: a systematic review and meta-analysis [J ] . Front Public Health , 2022 , 10 : 892973 .
Zhou X , Li XL , Ding H , et al . Acupuncture effects on in-vitro fertilization pregnancy outcomes: a meta-analysis [J ] . Complement Ther Clin Pract , 2022 , 46 : 101525 .
Moher D , Liberati A , Tetzlaff J , et al . Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement [J ] . PLoS Med , 2009 , 6 ( 7 ): e1000097 .
Shea BJ , Reeves BC , Wells G , et al . AMSTAR 2: a critical appraisal tool for systematic reviews that include randomised or non-randomised studies of healthcare interventions, or both [J ] . BMJ , 2017 , 358 : j4008 .
Atkins D , Best D , Briss PA , et al . Grading quality of evidence and strength of recommendations [J ] . BMJ , 2004 , 328 ( 7454 ): 1490 .
Gordon H.Guyatt , Andrew D.Oxman , Gunn Vist , 等 . GRADE指南:Ⅳ .证据质量分级——研究的局限性(偏倚风险)[J ] . 中国循证医学杂志 , 2011 , 11 ( 4 ): 456 - 463 .
Gordon H.Guyatt , Andrew D.Oxman , Regina Kunz , 等 . GRADE指南:Ⅶ .证据质量评价——不一致性[J ] . 中国循证医学杂志 , 2011 , 11 ( 12 ): 1444 - 1451 .
Gordon Guyatt , Andrew D.Oxman , Regina Kunz , 等 . GRADE指南:Ⅷ .证据质量评价——间接性[J ] . 中国循证医学杂志 , 2011 , 11 ( 12 ): 1452 - 1458 .
Gordon Guyatt , Andrew D.Oxman , Regina Kunz , 等 . GRADE指南:Ⅵ .证据质量评价——不精确性(随机误差)[J ] . 中国循证医学杂志 , 2011 , 11 ( 12 ): 1435 - 1443 .
Gordon H.Guyatt , Andrew D.Oxman , Victor Montori , 等 . GRADE指南:Ⅴ . 证据质量评价——发表偏倚[J ] . 中国循证医学杂志 , 2011 , 11 ( 12 ): 1430 - 1434 .
El-Toukhy T , Sunkara SK , Khairy M , et al . A systematic review and meta-analysis of acupuncture in in vitro fertilisation [J ] . BJOG , 2008 , 115 ( 10 ): 1203 - 1213 .
Manheimer E , Zhang G , Udoff L , et al . Effects of acupuncture on rates of pregnancy and live birth among women undergoing in vitro fertilisation: systematic review and meta-analysis [J ] . BMJ , 2008 , 336 ( 7643 ): 545 - 549 .
俞桔 . 针刺对体外受精-胚胎移植结局影响的系统评价 [D ] . 哈尔滨 : 黑龙江中医药大学 , 2009 .
El-Toukhy T , Khalaf Y . The impact of acupuncture on assisted reproductive technology outcome [J ] . Curr Opin Obstet Gynecol , 2009 , 21 ( 3 ): 240 - 246 .
Qu F , Zhou J , Ren RX . Effects of acupuncture on the outcomes of in vitro fertilization: a systematic review and meta-analysis [J ] . J Altern Complement Med , 2012 , 18 ( 5 ): 429 - 439 .
Zheng CH , Huang GY , Zhang MM , et al . Effects of acupuncture on pregnancy rates in women undergoing in vitro fertilization: a systematic review and meta-analysis [J ] . Fertil Steril , 2012 , 97 ( 3 ): 599 - 611 .
Cheong YC , Dix S , Hung Yu Ng E , et al . Acupuncture and assisted reproductive technology [J ] . Cochrane Database Syst Rev , 2013 ( 7 ): CD006920 .
Manheimer E , van der Windt D , Cheng K , et al . The effects of acupuncture on rates of clinical pregnancy among women undergoing in vitro fertilization: a systematic review and meta-analysis [J ] . Hum Reprod Update , 2013 , 19 ( 6 ): 696 - 713 .
沈春娟 . 针灸治疗对胚胎移植妊娠结果影响的Meta分析 [D ] . 武汉 : 华中科技大学 , 2014 .
姚韧敏 , 林淑员 . 针刺疗法在辅助生殖技术中应用系统评价 [C ] // 第六届国际中医妇科学术大会论文集 , 2015 : 258 - 261 .
Shen CJ , Wu MX , Shu DF , et al . The role of acupuncture in in vitro fertilization: a systematic review and meta-analysis [J ] . Gynecol Obstet Invest , 2015 , 79 ( 1 ): 1 - 12 .
杨会生 , 房繄恭 , 李晓彤 , 等 . 针灸对体外受精-胚胎移植患者妊娠结局影响的随机对照试验系统评价 [J ] . 中华中医药杂志 , 2017 , 32 ( 12 ): 5591 - 5598 .
Jo J , Lee YJ . Effectiveness of acupuncture in women with polycystic ovarian syndrome undergoing in vitro fertilisation or intracytoplasmic sperm injection: a systematic review and meta-analysis [J ] . Acupunct Med , 2017 , 35 ( 3 ): 162 - 170 .
Qian Y , Xia XR , Ochin H , et al . Therapeutic effect of acupuncture on the outcomes of in vitro fertilization: a systematic review and meta-analysis [J ] . Arch Gynecol Obstet , 2017 , 295 ( 3 ): 543 - 558 .
Schwarze JE , Ceroni JP , Ortega-Hrepich C , et al . Does acupuncture the day of embryo transfer affect the clinical pregnancy rate? Systematic review and meta-analysis [J ] . JBRA Assist Reprod , 2018 , 22 ( 4 ): 363 - 368 .
Zhang X , Lee MS , Smith CA , et al . Effects of acupuncture during in vitro fertilization or intracytoplasmic sperm injection: an updated systematic review and meta-analysis [J ] . Eur J Integr Med , 2018 , 23 : 14 - 25 .
Gu YE , Zhang X , Zhang Q , et al . The effects of acupuncture on pregnancy outcomes of in vitro fertilization with embryo transfer: an interdisciplinary systematic review [J ] . J Gynecol Obstet Hum Reprod , 2019 , 48 ( 8 ): 677 - 684 .
Smith CA , Armour M , Shewamene Z , et al . Acupuncture performed around the time of embryo transfer: a systematic review and meta-analysis [J ] . Reprod Biomed Online , 2019 , 38 ( 3 ): 364 - 379 .
Xie ZY , Peng ZH , Yao B , et al . The effects of acupuncture on pregnancy outcomes of in vitro fertilization: a systematic review and meta-analysis [J ] . BMC Complement Altern Med , 2019 , 19 ( 1 ): 131 .
尹萍 , 李丽 , 路璐 , 等 . 针刺联合辅助生殖技术对多囊卵巢综合征患者临床妊娠结局影响的Meta分析及GRADE质量评价 [J ] . 中华中医药杂志 , 2020 , 35 ( 2 ): 854 - 858 .
张夏菲 . 针灸对体外受精-胚胎移植患者妊娠结局影响的meta分析 [D ] . 成都 : 成都中医药大学 , 2020 .
Coyle ME , Stupans I , Abdel-Nour K , et al . Acupuncture versus placebo acupuncture for in vitro fertilisation: a systematic review and meta-analysis [J ] . Acupunct Med , 2021 , 39 ( 1 ): 20 - 29 .
Jang S , Kim KH , Jun JH , et al . Acupuncture for in vitro fertilization in women with poor ovarian response: a systematic review [J ] . Integr Med Res , 2020 , 9 ( 2 ): 100395 .
詹绪新 , 蔡鸿财 , 王勇 , 等 . 经皮穴位电刺激对体外授精-胚胎移植妊娠结局的影响:随机对照试验的meta分析 [J ] . 中华男科学杂志 , 2021 , 27 ( 9 ): 825 - 832 .
Li ML , Liu YY , Wang HR , et al . The effects of acupuncture on pregnancy outcomes of recurrent implantation failure: a systematic review and meta-analysis [J ] . Evid Based Complement Alternat Med , 2021 , 2021 : 6661235 .
Myung Lee Bussell . 针灸治疗不孕症理论和应用的研究 [D ] . 广州 : 广州中医药大学 , 2015 .
李静 , 李幼平 . 不断完善与发展的Cochrane系统评价 [J ] . 中国循证医学杂志 , 2008 , 8 ( 9 ): 742 - 743 .
周俊 , 李涓 , 叶静 , 等 . 应用AMSTAR及GRADE系统对针灸治疗变应性鼻炎的系统评价再评价 [J ] . 中国中西医结合杂志 , 2020 , 40 ( 7 ): 846 - 853 .
Moher D , Jadad AR , Nichol G , et al . Assessing the quality of randomized controlled trials: an annotated bibliography of scales and checklists [J ] . Control Clin Trials , 1995 , 16 ( 1 ): 62 - 73 .
0
浏览量
0
下载量
1
CSCD
关联资源
相关文章
相关作者
相关机构
京公网安备11010802024621