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1.成都中医药大学针灸推拿学院,四川成都 610075
2.贵州中医药大学针灸推拿学院, 贵阳 550025
3.贵州中医药大学第一附属医院 康复科
4.贵州中医药大学第一附属医院 针灸科,贵阳 550001
朱敏,成都中医药大学博士研究生。E-mail:944518618@qq.com
崔瑾,教授。E-mail:516260179@qq.com
收稿:2023-10-05,
网络首发:2024-02-02,
纸质出版:2024-04-12
移动端阅览
朱敏,全菲,薛凯阳,等.针刺治疗勃起功能障碍:随机对照试验[J].中国针灸,2024,44(4):418-422.
ZHU Min,QUAN Fei,XUE Kaiyang,et al.Acupuncture for erectile dysfunction: a randomized controlled trial[J].Chinese Acupuncture & Moxibustion,2024,44(04):418-422.
朱敏,全菲,薛凯阳,等.针刺治疗勃起功能障碍:随机对照试验[J].中国针灸,2024,44(4):418-422. DOI: 10.13703/j.0255-2930.20231005-0001.
ZHU Min,QUAN Fei,XUE Kaiyang,et al.Acupuncture for erectile dysfunction: a randomized controlled trial[J].Chinese Acupuncture & Moxibustion,2024,44(04):418-422. DOI: 10.13703/j.0255-2930.20231005-0001.
目的
2
观察针刺治疗勃起功能障碍(ED)的临床疗效。
方法
2
将64例ED患者随机分为针刺组(32例,脱落2例)和西药组(32例,脱落2例)。针刺组给予针刺治疗,穴取百会、气海、关元、中极、大赫、曲骨、足三里等两组穴位,交替使用,每次30 min,隔日1次;西药组于性活动前1 h 口服枸椽酸西地那非片50 mg。两组均治疗30 d。观察两组患者治疗前后及治疗结束后2周(随访)国际勃起功能量表( IIEF-5)评分、焦虑自评量表(SAS)评分、抑郁自评量表(SDS)评分、中医证候评分,检测治疗前后血清睾酮(T)含量,并评定两组临床疗效。
结果
2
治疗后及随访时两组患者IIEF-5评分较治疗前升高(
P<
0.01);随访时针刺组患者 IIEF-5评分高于西药组(
P<
0.05)。除西药组随访时SDS评分、中医证候评分,两组患者治疗后和随访时SAS、SDS评分及中医证候评分均较治疗前降低(
P<
0.01,
P<
0.05);治疗后和随访时针刺组SAS、SDS评分及中医证候评分低于西药组(
P<
0.01)。治疗后两组患者血清T含量较治疗前升高(
P<
0.01)。针刺组总有效率为83.3%(25/30),与西药组[86.7%(26/30)]比较差异无统计学意义(
P>
0.05)。
结论
2
针刺可改善 ED患者勃起功能、焦虑抑郁状态和中医证候;与西药治疗相比,具有后效应优势。
Objective
2
To observe the clinical efficacy of acupuncture in treating erectile dysfunction (ED).
Methods
2
A total of 64 ED patients were randomly divided into an acupuncture group (32 cases
2 case dropped out) and a western medication group (32 cases
2 cases dropped out). In the acupuncture group
acupuncture treatment was applied at Baihui (GV 20)
Qihai (CV 6)
Guanyuan (CV 4)
Zhongji (CV 3)
Dahe (KI 12)
Qugu (CV 2)
Zusanli (ST 36)
and etc.
two groups of acupoints were used alternately
30 min each time
once every other day. In the western medication group
50 mg of sildenafil tablet was took orally 1 h before sexual activity. Both groups were treated for 30 d. The international index of erectile function citrate (IIEF-5) score
self rating anxiety scale (SAS) score
self rating depression scale (SDS) score
TCM syndrome score were observed before and after treatment
and in follow-up of 2 weeks after treatment completion
the serum testosterone (T) level was detected before and after treatment
and the clinical efficacy was evaluated in the two groups.
Results
2
After treatment and in follow-up
the IIEF-5 scores were increased compared with those before treatment in the two groups (
P<
0.01). In follow-up
the IIEF-5 score in the acupuncture group was ascended compared with that in the western medication group (
P<
0.05). Except for the SDS and TCM syndrome scores in the western medication group of follow-up
the SAS scores
SDS scores
and the TCM syndrome scores were decreased after treatment and in follow-up compared with those before treatment in the two groups (
P
<
0.01
P
<
0.05); in the acupuncture group
the SAS scores
SDS scores and the TCM syndrome scores after treatment and in follow-up were lower than those in the western medication group (
P
<
0.01). After treatment
the serum T levels were increased compared with those before treatment in the two groups (
P
<
0.01). The total effective rate of the acupuncture group was 83.3% (25/30)
and it was 86.7% (26/30) in the western medication group
there was no significant difference in total effective rate between the two groups (
P
>
0.05).
Conclusion
2
Acupuncture can effectively improve erectile function
anxiety and depression state
and TCM syndrome in ED patients
and has a advantage of posterior effect compared with western medication treatment.
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