耳穴贴压联合眼周揿针技术预防假性近视向真性近视进展：多中心随机对照试验

侯昕玥; 王健全; 亢泽峰; 杨迎新; 姚小萍; 张风梅; 姚靖; 喻京生; 刘新泉; 梁凤鸣; 俞晓艺; 宋曼

doi:10.13703/j.0255-2930.20231122-0004

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耳穴贴压联合眼周揿针技术预防假性近视向真性近视进展：多中心随机对照试验

临床研究 | 更新时间：2024-06-03

- 耳穴贴压联合眼周揿针技术预防假性近视向真性近视进展：多中心随机对照试验
- Pseudomyopia treated with auricular point sticking combined with periocular needle-embedding therapy and prevention of true myopia: a multicenter randomized controlled trial
- 中国针灸 2024年44卷第4期页码：405-410
- 作者机构：
  
  1.中国中医科学院眼科医院，北京 100040
  2.中国中医科学院，北京 100040
  3.首都医科大学附属北京中医医院
  4.深圳市中医院
  5.河南省中医院
  6.黑龙江中医药大学附属第一医院
  7.湖南中医药大学第一附属医院
  8.上海中医药大学附属龙华医院
  9.天津中医药大学第一附属医院
  10.广州中医药大学第一附属医院
  11.福建中医药大学附属福州中医院
- 作者简介：
  
  亢泽峰，主任医师、教授。E-mail：zefeng2531@163.com
- 基金信息：
- DOI：10.13703/j.0255-2930.20231122-0004
  中图分类号：
- 收稿：2023-11-22，
  
  网络首发：2024-02-02，
  
  纸质出版：2024-04-12
- 稿件说明：
移动端阅览
侯昕玥,王健全,亢泽峰,等.耳穴贴压联合眼周揿针技术预防假性近视向真性近视进展：多中心随机对照试验[J].中国针灸,2024,44(4):405-410.

HOU Xinyue,WANG Jianquan,KANG Zefeng,et al.Pseudomyopia treated with auricular point sticking combined with periocular needle-embedding therapy and prevention of true myopia: a multicenter randomized controlled trial[J].Chinese Acupuncture & Moxibustion,2024,44(04):405-410.
侯昕玥,王健全,亢泽峰,等.耳穴贴压联合眼周揿针技术预防假性近视向真性近视进展：多中心随机对照试验[J].中国针灸,2024,44(4):405-410. DOI： 10.13703/j.0255-2930.20231122-0004.

HOU Xinyue,WANG Jianquan,KANG Zefeng,et al.Pseudomyopia treated with auricular point sticking combined with periocular needle-embedding therapy and prevention of true myopia: a multicenter randomized controlled trial[J].Chinese Acupuncture & Moxibustion,2024,44(04):405-410. DOI： 10.13703/j.0255-2930.20231122-0004.

摘要

目的

观察耳穴贴压联合眼周揿针技术预防假性近视发展成为真性近视的临床疗效及安全性。

方法

将269例假性近视患儿随机分为观察组（134例，脱落2例）与对照组（135例，脱落5例）。对照组予健康宣教；观察组在对照组基础上予耳穴贴压（肝、脾、心、眼，每次取单侧耳穴）联合眼周揿针（双侧攒竹、鱼腰、四白）干预，治疗4周后休息2周，6周为一疗程，共治疗2个疗程。分别于治疗前、治疗6周、治疗12周及治疗结束后12周（第1次随访）、24周（第2次随访）观察两组患儿等效球镜（SE）及SE进展量、眼轴（AL）进展量、调节幅度（AMP）、中医症状和全身症状评分，并评价安全性及依从性。

结果

治疗6、12周及第1、2次随访，两组患儿SE较治疗前增长（

0.05），观察组患儿AMP较治疗前升高（

0.05）。治疗12周及第1、2次随访，观察组患儿SE进展量低于对照组（

0.01，

0.001）；治疗6、12周及第1、2次随访，观察组患儿AL进展量低于对照组（

0.05，

0.01，

0.001）；第1、2次随访，观察组患儿AMP高于对照组（

0.05，

0.001）。治疗6、12周及第1、2次随访，观察组患儿中医症状和全身症状总分较治疗前降低（

0.05）；治疗6、12周，对照组患儿中医症状和全身症状总分较治疗前降低（

0.05）。观察组患儿第1、2次随访中医症状和全身症状总分差值大于对照组（

0.05）；第1、2次随访面色淡白/晦暗评分及第2次随访神疲乏力评分低于对照组（

0.05）；治疗12周注意力下降评分及第2次随访睡眠不佳、记忆力下降评分低于对照组（

0.05）。两组均无不良反应发生，观察组依从性为98.5%，对照组为96.3%，两组依从性比较差异无统计学意义（

0.05）。

结论

在健康宣教基础上，耳穴贴压联合眼周揿针技术可有效预防假性近视向真性近视进展，控制SE增加、延缓AL增长、增加AMP，且能改善全身症状，从多途径综合预防近视，安全性高，依从性好。

Abstract

Objective

To observe the clinical effect and safety of auricular point sticking combined with periocular needle-embedding therapy for pseudomyopia and prevention of true myopia.

Methods

A total of 269 children with pseudomyopia were randomized into an observation group (134 cases

2 cases dropped out) and a control group (135 cases

5 cases dropped out). In the control group

the healthy education was provided. In the observation group

besides the intervention as the control group

the auricular point sticking was delivered at gan (CO

)

pi (CO

)

xin (CO

) and yan (LO

) on one ear in each treatment

combined with periocular needle-embedding technique at bilateral Cuanzhu (BL 2)

Yuyao (EX-HN 4) and Sibai (ST 2). There were 2 weeks of interval after 4 weeks of treatment. One course of treatment was composed of 6 weeks and 2 courses were required. Separately

before treatment

after 6 and 12 weeks of treatment

and after 12 weeks (the 1st follow-up visit) and 24 weeks (the 2nd follow-up visit) of treatment completion

the spherical equivalent (SE)

SE progression

axial length (AL) progression

accommodative amplitude (AMP)

the score of the TCM symptom and the general symptom were observed in the two groups. The safety and compliance were evaluated in the two groups.

Results

After 6 and 12 weeks of treatment

and in the 1st and 2nd follow-up visits

SE increased when compared with that before treatment in the two groups (

0.05)

and AMP was larger than that before treatment in the observation group (

0.05). After 12 weeks of treatment

and in the 1st and 2nd follow-up visits

the progression of SE was slower in the observation group compared with that in the control group (

0.01

0.001). After 6 and 12 weeks of treatment

and in the 1st and 2nd follow-up visits

the progression of AL in the observation group was lower than that of the control group (

0.05

0.01

0.001); and in the 1st and 2nd follow-up visits

AMP of the observation group was larger when compared with that in the control group (

0.05

0.001). After 6 and 12 weeks of treatment

and in the 1st and 2nd follow-up visits

the total scores of TCM symptom and general symptom were reduced in comparison with those before treatment in the observation group (

0.05); after 6 and 12 weeks of treatment

the total scores of TCM symptom and general s

ymptom were lower than those before treatment in the control group (

0.05). In the 1st and 2nd follow-up visits

the difference of the total score of TCM symptom and general symptom in the observation group was larger than that of the control group (

0.05). In the observation group

compared with the control group

the scores for pale/dark complexion in the 1st and 2nd follow-up visits and that for lassitude in the 2nd follow-up visit were lower (

0.05)

the score for poor concentration after 12 weeks of treatment and that for poor sleep and memory in the 2nd follow-up visit were lower (

0.05). There were no adverse reactions in the two groups. The compliance was 98.5% in the observation group and was 96.3% in the control group

without statistical difference (

0.05).

Conclusion

On the basis of health education

auricular point sticking combined with periocular needle-embedding therapy can effectively prevent from true myopia

control the increase of SE

delay the growth of AL and improve AMP in children with pseudomyopia. This compound therapeutic regimen can relieve the general symptom and comprehensively prevent from myopia through multiple approaches

with high safety and satisfactory compliance.

关键词

Keywords

references

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