The correlation between meridians and

zangfu

organs is one of the core contents of the theory of

zangfu

organs and meridians

which has significant research value and clinical application potential. In this paper

the research literature on correlation between meridians and

zangfu

organs in the past five years is sorted out and summarized

and it is found that more clinical application basis is added in meridian-diagnosis

and a new situation of high-quality evidence-based medicine is opened in the aspect of meridian-treatment. In terms of internal connection and biological mechanism

the neurobiological characteristics and regulatory mechanism represented by "heart meridian-heart" are illustrated. The research model of the relationship between the meridians-

zangfu

organs and the brain

which combines the functional connection of the brain network in clinic and the basic neural circuit mechanism under the premise of the "effect law"

is clearly proposed.