浮针治疗非急性期特发性面神经麻痹：随机对照试验

陶腊梅; 李静; 陆瑾; 朱茂慧; 谢志红; 包小丽; 丁星浩

doi:10.13703/j.0255-2930.20240611-k0001

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浮针治疗非急性期特发性面神经麻痹：随机对照试验

临床研究 | 更新时间：2024-11-14

- 浮针治疗非急性期特发性面神经麻痹：随机对照试验
- Fuʹs subcutaneous needling for non-acute idiopathic facial paralysis : a randomized controlled trial
- 中国针灸 2024年44卷第11期页码：1249-1253
- 作者机构：
  
  1.南京中医药大学附属南京中医院/南京市中医院针灸科，江苏　南京　210022
  2.南京市浦口区中医院康复科
  3.滁州市中西医结合医院针灸二科
  4.南京中医药大学
  5.南京靖安社区卫生服务中心针灸科
- 作者简介：
  
  ✉李静，主任中医师。E-mail：fsyy00305@njucm.edu.cn
- 基金信息：
  
  江苏省中医药管理局中医药科技发展计划面上项目(MS2021035);南京市名中医工作室项目(LJ-2017-NJ);南京市名中医工作室基层工作站项目(LJ-2021-SJJCGZZ)
- DOI：10.13703/j.0255-2930.20240611-k0001
  中图分类号：
- 收稿：2024-06-11，
  
  网络首发：2024-08-28，
  
  纸质出版：2024-11-12
- 稿件说明：
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陶腊梅, 李静, 陆瑾, 等. 浮针治疗非急性期特发性面神经麻痹：随机对照试验[J]. 中国针灸, 2024,44(11):1249-1253.

TAO Lamei, LI Jing, LU Jin, et al. Fuʹs subcutaneous needling for non-acute idiopathic facial paralysis : a randomized controlled trial[J]. Chinese Acupuncture & Moxibustion, 2024, 44(11): 1249-1253. DOI: 10.13703/j.0255-2930.20240611-k0001.
陶腊梅, 李静, 陆瑾, 等. 浮针治疗非急性期特发性面神经麻痹：随机对照试验[J]. 中国针灸, 2024,44(11):1249-1253. DOI： 10.13703/j.0255-2930.20240611-k0001.

TAO Lamei, LI Jing, LU Jin, et al. Fuʹs subcutaneous needling for non-acute idiopathic facial paralysis : a randomized controlled trial[J]. Chinese Acupuncture & Moxibustion, 2024, 44(11): 1249-1253. DOI: 10.13703/j.0255-2930.20240611-k0001. DOI：

摘要

目的：

观察浮针治疗非急性期特发性面神经麻痹的临床疗效及对血清一氧化氮（NO）、内皮素（ET）含量的影响。

方法：

将76例非急性期特发性面神经麻痹患者随机分为观察组（38例，脱落2例）和对照组（38例，脱落2例）。对照组予基础治疗（口服甲钴胺片、特定电磁波谱照射、面肌康复训练），观察组在对照组的基础上予浮针治疗，进针点包括肱桡肌、胸锁乳突肌、斜方肌等，于患肌周边进针，扫散同时配合再灌注活动，隔日1次，每周3次。两组均治疗4周。分别于治疗前及治疗2、4周后观察两组患者House-Brackmann（H-B）分级、H-B症状评分，比较两组患者治疗前、治疗4周后面部残疾指数（FDI）评分[包括躯体功能（FDIP）评分和社会生活功能（FDIS）评分]及血清NO、ET含量，并比较两组患者临床疗效和安全性。

结果：

治疗2、4周后，两组患者H-B分级较治疗前降低、H-B症状评分较治疗前升高（

0.001，

0.05），且观察组H-B分级低于对照组、H-B症状评分高于对照组（

0.01，

0.05）。治疗4周后，两组患者FDIP评分均较治疗前升高、FDIS评分均较治疗前降低（

0.05），且观察组FDIP评分高于对照组、FDIS评分低于对照组（

0.05）。治疗4周后，观察组患者血清NO含量较治疗前升高、ET含量较治疗前降低（

0.05），观察组血清NO含量升高幅度、ET含量降低幅度大于对照组（

0.05）。观察组治愈率为55.6%（20/36），高于对照组的22.2%（8/36，

0.05）。两组均未出现严重不良反应。

结论：

浮针配合基础治疗可有效改善非急性期特发性面神经麻痹患者面肌运动功能，可能与调节血清NO、ET含量有关。

Abstract

Objective

To observe the effect of

's subcutaneous needling in the treatment of non-acute idiopathic facial paralysis and its effect on serum levels of nitric oxide (NO) and endothelin (ET).

Methods

A total of 76 patients with non-acute idiopathic facial paralysis were randomly divided into an observation group (38 cases

2 cases dropped out) and a control group (38 cases

2 cases dropped out). The patients in the control group received basic treatment (mecobalamin tablets orally

specific electromagnetic spectrum irradiation

facial muscle rehabilitation training). The patients in the observation group were treated with

's subcutaneous needling on the basis of the control group. The needling points included brachioradialis muscle

sternocleidomastoid muscle

trapezius muscle

etc.

and the needling was inserted around the affected muscle

and the reperfusion activity was carried out at the same time

once every other day

3 times a week. Both groups were treated for 4 weeks. The House-Brackmann (H-B) grade and H-B symptom score were observed before treatment

after 2 and 4 weeks of treatment in the two groups. The facial disability index (FDI) score [including physical function (FDIP) score and social life function (FDIS) score

]

and the serum levels of NO and ET were compared before and after 4 weeks of treatment in the two groups. The clinical effect and safety of the two groups were assessed.

Results

After 2 and 4 weeks of treatment

the H-B grade of the two groups was lower than that before treatment

and the H-B symptom scores were higher than those before treatment (

0.001

0.05); the H-B grade of the observation group was lower than that of the control group

and the H-B symptom score was higher than that of the control group (

0.01

0.05). After 4 weeks of treatment

the FDIP scores of the two groups were higher than those before treatment

and the FDIS scores were lower than those before treatment (

0.05 ); the FDIP score of the observation group was higher than that of the control group

and the FDIS score was lower than that of the control group (

0.05). After 4 weeks of treatment

the serum level of NO in the observation group was higher than that before treatment

and the serum level of ET was lower than that before treatment (

0.05); the increase of serum level of NO and the decrease of serum level of ET in the observation group were greater than those in the control group (

0.05). The cure rate of th

e observation group was 55.6% (20/36)

which was higher than 22.2% (8/36) of the control group (

0.05). There were no serious adverse reactions in both groups.

Conclusion

's subcutaneous needling combined with basic treatment can effectively improve the motor function of facial muscles in patients with non-acute idiopathic facial paralysis

which may be related to the regulation of serum NO and ET levels.

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