The clinical research system of acupuncture and moxibustion has gradually developed and matured to a certain scale

but there is still a large space for improvement. This paper summarizes the new concepts and designs of clinical research

emerging in recent years

including "patient-centered" clinical study and digital clinical research

as well as the design methods like master protocol and enrichment design. The related contents that can be adopted for reference in clinical research of acupuncture and moxibustion are expounded

to provide enlightenment and reference for future clinical research and drive the innovation and improvement of clinical research of acupuncture and moxibustion.