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河北中医药大学研究生学院,石家庄 050091
河北省中医院康复科,石家庄 050011
平山县中医院康复科
刘卓灿,河北中医药大学硕士研究生。E-mail:2580855650@qq.com
✉张振伟,教授、主任医师。E-mail:zzw71@qq.com
收稿:2024-09-02,
网络首发:2025-06-12,
纸质出版:2025-10-12
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刘卓灿, 李娜, 陈超, 等. 基于数据挖掘技术分析针灸干预孤独症谱系障碍的选穴规律[J]. 中国针灸, 2025,45(10):1496-1504.
LIU Zhuocan, LI Na, CHEN Chao, et al. Analysis of acupoint selection rules for acupuncture for autism spectrum disorder based on data mining technology[J]. Chinese Acupuncture & Moxibustion, 2025, 45(10): 1496-1504.
刘卓灿, 李娜, 陈超, 等. 基于数据挖掘技术分析针灸干预孤独症谱系障碍的选穴规律[J]. 中国针灸, 2025,45(10):1496-1504. DOI: 10.13703/j.0255-2930.20240902-0003.
LIU Zhuocan, LI Na, CHEN Chao, et al. Analysis of acupoint selection rules for acupuncture for autism spectrum disorder based on data mining technology[J]. Chinese Acupuncture & Moxibustion, 2025, 45(10): 1496-1504. DOI: 10.13703/j.0255-2930.20240902-0003.
目的:
2
基于数据挖掘技术分析针灸干预孤独症谱系障碍(ASD)的核心选穴及辨证配伍规律。
方法:
2
检索中国期刊全文数据库(CNKI)、万方数据知识服务平台(Wanfang)、维普资讯中文期刊服务平台(VIP)、PubMed、Web of Science中针灸治疗ASD的相关文献,根据纳入与排除标准,提取有效信息后建立处方数据库。对腧穴的频次、归经、分布部位、特定穴进行描述性分析;Origin软件绘制高频腧穴图;IBM SPSS Modeler 18.0软件Apriori 算法对处方中腧穴进行关联规则分析;IBM SPSS Statistics 26.0软件对高频腧穴进行聚类分析;Cytoscape 3.10.0软件实现高频证型与腧穴间关系的可视化处理。
结果:
2
纳入文献223篇,涉及处方452条,其中辨证取穴处方223条,腧穴共205个,总频次4 067次;腧穴使用频次前5位依次为百会、四神针、智三针、颞三针和内关;选穴多为靳三针、督脉、头针和足太阳膀胱经腧穴,头颈部和四肢腧穴占比较高,特定穴中五输穴、原穴和背俞穴使用频次较高;关联规则表明四神针-定神针-智三针-颞三针为核心穴组;前20位高频腧穴聚类分析分为4类,分别为通督醒脑组、健脾养心组、靳三针调神组和益肾填髓组;临床以肾精亏虚、心肝火旺、痰蒙心窍、心脾两虚、肝郁气滞5种证型为主。
结论:
2
针灸治疗ASD的核心腧穴处方是四神针、定神针、智三针、颞三针,重视调神治神,以多脏腑同调、调和气血,兼以畅气机、平衡阴阳为其治疗原则,临证可辨证配穴。
Objective
2
To analyze the core acupoint selection rules and syndrome-based compatibility patterns of acupuncture for autism spectrum disorder (ASD) using data mining techniques.
Methods
2
Relevant literature of acupuncture for ASD was retrieved from CNKI
Wanfang
VIP
PubMed
and Web of Science. After applying inclusion and exclusion criteria
a prescription database was established based on the extracted effective data. Descriptive analysis was conducted on the frequency
meridian tropism
anatomical distribution
and specific point. High-frequency acupoints were visualized using Origin software. The Apriori algorithm in IBM SPSS Modeler 18.0 was used for association rule analysis of acupoint combinations. Cluster analysis of high-frequency acupoints was performed using IBM SPSS Statistics 26.0. The relationships between high-frequency syndromes and acupoints were visualized using Cytoscape 3.10.0.
Results
2
A total of 223 studies and 452 prescriptions were included
among which 223 were based on syndrome differentiation. A total of 205 acupoints were included with a cumulative frequency of 4 067. The top five most frequently used acupoints were Baihui (GV20)
Sishenzhen
Zhisanzhen
Niesanzhen
and Neiguan (PC6). Acupoints were primarily from
Jin
’s three-needle therapy
the governor vessel
scalp acupuncture
and the foot-
taiyang
bladder meridian
with a high proportion of acupoints located on the head and neck and the limbs. Among specific point
five-
shu
points
yuan
-source points
and back-
shu
points were most frequently used. Association rule analysis revealed that the core acupoint group was Sishenzhen-Dingshenzhen-Zhisanzhen-Niesanzhen. Cluster analysis divided the top 20 high-frequency acupoints into four categories: governor vessel activation and brain awakening group
spleen strengthening and heart nourishing group
Jin
’s three-needle spirit-regulating group
and kidney-reinforcing and marrow-filling group. Cli
nically
the main syndrome patterns were kidney essence deficiency
hyperactivity of heart and liver fire
phlegm obstructing the heart orifices
dual deficiency of heart and spleen
and liver
qi
stagnation.
Conclusion
2
The core acupoint prescriptions of acupuncture for ASD are Sishenzhen
Dingshenzhen
Zhisanzhen
and Niesanzhen. The treatment emphasizes spirit regulation and mental tranquility
guided by the principles of harmonizing multiple
zang
-
fu
organs
regulating
qi
and blood
unblocking
qi
movement
and balancing
yin
and
yang
. Syndrome-based acupoint compatibility is recommended in clinical practice.
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