AN Shuya, LAN Tian, Tseng Yiider. Treatment mechanism of the thermal stimuli of moxibustion on rheumatoid arthritis based on the responses of primary lesion cells to temperature[J]. Chinese Acupuncture & Moxibustion, 2026, 46(5): 846-852.
AN Shuya, LAN Tian, Tseng Yiider. Treatment mechanism of the thermal stimuli of moxibustion on rheumatoid arthritis based on the responses of primary lesion cells to temperature[J]. Chinese Acupuncture & Moxibustion, 2026, 46(5): 846-852.DOI: 10.13703/j.0255-2930.20241009-0002.
This study reviews the pathological behaviors of the primary lesion cells in rheumatoid arthritis
including fibroblasts-like synoviocyte
macrophages
and T cells during the progression of the disease. It analyzes the effects of temperature on phenotypic remodeling and molecular signaling pathways of the relevant cells. After deeply exploring the action mechanism of the thermal stimuli of moxibustion on rheumatoid arthritis
it is found that during moxibustion
the different temperatures of moxibustion may influence the primary lesion cells in rheumatoid arthritis by activating different thermosensitive proteins and thermosensitive pathways