The paper explores the etiology and pathogenesis of chronic fatigue syndrome (CFS)

and its diagnosis and treatment with acupuncture and moxibustion based on "body-

qi

-mind trinity life view". It is believed that CFS refers to the comorbidity of body

qi

and mind. In the disease

spleen deficiency in transportation and transformation is the root

resulting in malnutrition of muscles; liver

qi

stagnation is the pivot

causing dysfunction of three

jiao

; and disharmony between heart and kidney is crucial

leading to dysfunction of mind. The strategy of treatment with acupuncture and moxibustion is proposed

"relieving general pain of the body as the top priority

regulating

qi

is the pivot

and housing the mind is the foundation". For relieving general pain of the body

acupuncture is ap

plied to Sanyinjiao (SP6) and Zusanli (ST36) that is the essential prescription to relieve muscular pain. For regulating

qi

Waiguan (TE5) and Gongsun (SP4) are selected to promote the pivot of

shaoyang

and regulate

qi

movement of three

jiao

. For housing the mind

acupuncture is delivered at Shenmen (HT7) and moxibustion is applied to Yongquan (KI1)

Gaohuang (BL43) and Baihui (GV20) to harmonize the heart and kidney and tranquilize the mind. This intervention mode

i.e. harmonizing among body

qi

and mind

and promoting the circulation of

qi

and blood

is conductive to restoring the body

qi

and mind. It provides a new idea to clinical diagnosis and treatment of CFS with acupuncture and moxibustion.