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江西中医药大学临床医学院,南昌 330006
江西中医药大学热敏灸转化医学研究中心
江西省戒毒管理局
江西省强制隔离戒毒所
江西省女子强制隔离戒毒所
江西中医药大学附属医院针灸科,南昌 330025
✉陈日新,教授。E-mail:chenrixin321@163.com
收稿:2025-04-02,
网络首发:2025-07-17,
纸质出版:2025-08-12
移动端阅览
江月霞, 李海燕, 何巍, 等. 热敏灸机器人改善甲基苯丙胺成瘾者(戒断期)抑郁状态:随机对照试验[J]. 中国针灸, 2025,45(8):1061-1067.
JIANG Yuexia, LI Haiyan, HE Wei, et al. Heat-sensitive moxibustion robot for improving depressive state in methamphetamine addicts during withdrawal period: a randomized controlled trial[J]. Chinese Acupuncture & Moxibustion, 2025, 45(8): 1061-1067.
江月霞, 李海燕, 何巍, 等. 热敏灸机器人改善甲基苯丙胺成瘾者(戒断期)抑郁状态:随机对照试验[J]. 中国针灸, 2025,45(8):1061-1067. DOI: 10.13703/j.0255-2930.20250402-k0001.
JIANG Yuexia, LI Haiyan, HE Wei, et al. Heat-sensitive moxibustion robot for improving depressive state in methamphetamine addicts during withdrawal period: a randomized controlled trial[J]. Chinese Acupuncture & Moxibustion, 2025, 45(8): 1061-1067. DOI: 10.13703/j.0255-2930.20250402-k0001.
目的:
2
观察热敏灸机器人改善甲基苯丙胺成瘾者(戒断期)抑郁状态的临床疗效。
方法:
2
将60例伴抑郁状态的甲基苯丙胺成瘾者随机分为观察组(40 例,脱落4例)和对照组(20例,脱落2例)。对照组予以强制隔离戒毒所常规健康教育及戒治活动;观察组在对照组的基础上采用热敏灸机器人在患者神阙、膻中探敏定位,施以双点雀啄灸,每次施灸 60 min,第1周施灸4次,第2周与第3周各施灸3次,第4周施灸2次,共12次。分别于治疗前,治疗第2、4周末,治疗结束后第4周末(随访)评估两组患者汉密尔顿抑郁量表(HAMD)、抑郁自评量表(SDS)、毒瘾渴求视觉模拟量表(VAS)、汉密尔顿焦虑量表(HAMA)、焦虑自评量表(SAS)和匹兹堡睡眠质量指数(PSQI)评分。
结果:
2
治疗后各时间点,观察组患者HAMD、VAS、HAMA和PSQI评分均低于治疗前(
P
<
0.01,
P
<
0.001);治疗第4周末和随访时,观察组患者SDS、SAS评分均低于治疗前(
P
<
0.001,
P
<
0.01)。治疗后各时间点,对照组患者上述评分与治疗前比较差异均无统计学意义(
P
>
0.05)。治疗后各时间点,观察组患者HAMD、VAS评分低于对照组(
P
<
0.01,
P
<
0.001,
P
<
0.05);治疗第4周末和随访时,观察组患者SDS、HAMA评分低于对照组(
P
<
0.05,
P
<
0.001);治疗第4周末,观察组患者PSQI评分低于对照组(
P
<
0.01)。
结论:
2
热敏灸机器人可有效改善甲基苯丙胺成瘾者抑郁状态、焦虑情绪及睡眠质量,减轻毒瘾渴求。
Objective
2
To observe the clinical efficacy of heat-sensitive moxibustion robot for improving the depressive state of methamphetamine addicts during withdrawal period.
Methods
2
A total of 60 patients with methamphetamine addiction accompanied with depressive state were randomly divided into an observation group (40 cases
4 cases dropped out) and a control group (20 cases
2 cases dropped out). The control group received routine health education and addiction treatment in compulsory isolation drug rehabilitation center. On the basis of the treatment in the control group
in the observation group
the heat-sensitive moxibustion robot was used to locate sensitive points at the Shenque (CV8) and Danzhong (CV17)
and dual-point sparrow-pecking moxibustion was delivered for 60 min per session. The moxibustion therapy was performed 4 times in the 1st week
3 times in the 2nd and 3rd weeks respectively
and 2 times in the 4th week
for 12 times totally. The scores of Hamilton depression scale (HAMD)
self-rating depression scale (SDS)
visual analogue scale (VAS) for drug craving
Hamilton anxiety scale (HAMA)
self-rating anxiety scale (SAS)
and Pittsburgh sleep quality index (PSQI) were observed before treatment
at the end of the 2nd and 4th weeks of treatment
and 4 weeks after the treatment completion (follow-up) in the two groups.
Results
2
At each time point after treatment
in the observation group
the HAMD
VAS
HAMA and PSQI scores were decreased compared with those before treatment (
P
<
0.01
P
<
0.001); at the end of the 4th week of treatment and in follow-up
the SDS and SAS scores were decreased compared with those before treatment (
P
<
0.001
P
<
0.01). Compared before treatment
there were no significant differences in the above scores at each time point after treatment in the control group (
P
>
0.05). In the observation group
at each time point after treatment
the HAMD and VAS scores were lower than those in the control group (
P
<
0.01
P
<
0.001
P
<
0.05); at the end of the 4th week of treatment and in follow-up
the SDS and HAMA scores were lower than those in the control group (
P
<
0.05
P
<
0.001); at the end of the 4th week of treatment
the PSQI score was lower than that in the control group (
P
<
0.01).
Conclusion
2
Heat-sensitive moxibustion robot effectively improves depression
anxiety and sleep quality
and reduces drug craving in methamphetamine addicts during withdrawal period.
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