A decade of breakthroughs in high-quality clinical research on acupuncture: deep transformation and paradigm reconstruction marching towards evidence-based medicine
WU Jiani, YANG Tao, LIU Zhishun. A decade of breakthroughs in high-quality clinical research on acupuncture: deep transformation and paradigm reconstruction marching towards evidence-based medicine[J]. Chinese Acupuncture & Moxibustion, 2026, 46(8): 1375-1386.
WU Jiani, YANG Tao, LIU Zhishun. A decade of breakthroughs in high-quality clinical research on acupuncture: deep transformation and paradigm reconstruction marching towards evidence-based medicine[J]. Chinese Acupuncture & Moxibustion, 2026, 46(8): 1375-1386.DOI: 10.13703/j.0255-2930.20250708-0003.
acupuncture clinical trials have achieved leapfrog development
from empirical medicine to evidence-based medicine. Many multicenter randomized controlled trials with rigorous designs and adequate sample sizes have been published in top-tier international journals including
The Journal of The American Medical Association
(
JAMA
)
British Medical Journal
(
BMJ
)
Annals of Internal Medicine
and
Journal of Clinical Oncology
(
JCO
). It has significantly enhanced the scientific credibility of acupuncture efficacy
leading the World Health Organization to include acupuncture in the Traditional Medicine Chapter of the 11th Revision of the International Classification of Diseases (ICD-11); and has prompted the inclusion of acupuncture therapy in the medical insurance system in many countries. The research hotspots focus on chronic pain
functional gastrointestinal diseases
urinary and pelvic floor dysfunction
supportive therapy for tumors
perioperative management
and neuropsychiatric disorders. Many findings have been cited in authoritative guidelines from both domestic and international sources
significantly elevating the status of acupuncture in the global healthcare system. The research paradigm of acupuncture in China is shifting from "verifying efficacy" to "optimizing pathways"
with greater emphasis on objective outcome indicators
long-term efficacy observation
and the accumulation of real-world data. In the future
the emerging technologies will be deeply integrated
such as artificial intelligence with big data and virtual/augmented reality. It is expected to further facilitate
the accumulation of high-quality evidence
the construction of precise prediction model of efficacy
and the innovation of intelligent diagnosis and treatment paradigms. It will propel acupuncture from a "supplementary therapy" to an integrative medicine
and reshape disciplinary research paradigms and international development frameworks.